Evidence map›Paper›PMID 41028301›Full record

ArticleScientific reports2025

Reconstruction of three-dimensional retinal shape from refractive topography data.

Zhaodi Ma, Lihua Fang, Chongchong Ma, Yutong Liu, Zhuang Guo, Yan Wang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zhaodi MaKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China.
Lihua FangKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China. fanglh71@126.com.
Chongchong MaKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China.
Yutong LiuSchool of Medicine, Nankai University, Tianjin, 300020, China.
Zhuang GuoKey Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang, 330063, China.
Yan WangTianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Nankai University Eye Institute, Nankai University, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, China. wangyan7143@vip.sina.com.

Funding

The National Key Research and Development Program of China 2022YFC2404502The Natural National Science Foundation of China (NSFC) 62165010
6 · The paper itself

Abstract

A three-dimensional retinal shape was reconstructed by refractive topography (RT).

methodsThe personalized optical models of the human eye were reconstructed based on geometric parameters from clinical measurements. The expected refraction distribution on the fundus was calculated for each model. Subsequently, the refraction-position conversion function (RPF) was derived by fitting the data sets, which included the field of view (FOV), vitreous thickness (VT), and refraction. Additionally, the coordinates on the fundus of the human eye were calculated from RT data through the RPF. Ultimately, a three-dimensional retinal shape was reconstructed.

resultsThe expected refraction was calculated on 6 subjects. The results demonstrate that the expected refraction decreased as the VT increased. However, when the FOV was greater than 8°, the expected refraction increased with increasing FOV. A polynomial was applied to fit the 656 data points, resulting in the formation of the RPF. The fitting results demonstrated that the relationship tended to be similar in general for different human eyes, but there were individual differences. This reconstructed method provided good agreement between the reconstructed three-dimensional retina shape and the OCT measurements.

conclusionThe reconstructed three-dimensional retinal shape from RT data enables new imaging protocols that improve visualization of retinal shape.

Indexed as

Imaging, Three-DimensionalRefraction, OcularRetinaAdultFemaleHumansMaleTomography, Optical Coherence

Identifiers

PMID41028301
PMCPMC12484720

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