ArticleScientific reports2025
Histologic evaluation of furcation perforation treated using bioceramic putty with and without platelet rich fibrin or chitosan hydrogel as an internal matrix.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study investigated the tissue reaction of platelet rich fibrin and chitosan hydrogel as internal matrices in repairing furcal perforations in mature dogs' teeth. Seventy-two teeth in six mongrel dogs were experimented in this study. After access opening, root canal preparation was completed and obturation was done using gutta percha/resin sealer. Furcation perforations were done, and the experimental teeth were classified according to the perforation repair protocol to three experimental groups and a positive control group (18 teeth each). Group 1: Platelet-rich fibrin matrix with premixed calcium silicate-based bioceramic putty (BC putty), Group 2: Chitosan hydrogel matrix with BC putty, Group 3: BC putty alone and Group 4: a positive control group where no repair material was utilized. Access openings were restored with composite filling. The experimented teeth and the supporting bone were sectioned into blocks and histologically examined for tissue reaction at one and three months. Statistical analysis was performed using Chi-square test, where the significance level was set at P ≤ 0.05. BC putty and BC putty with PRF matrix exhibited less bone loss, epithelial proliferation and inflammatory reaction compared to chitosan hydrogel at one and three months intervals, also they showed more hard tissue deposition compared to chitosan hydrogel at 3-month interval. Although BC putty presented higher sealing ability with great area of newly formed hard tissue compared to chitosan hydrogel, BC putty with PRF can be considered as a successful management option for furcal perforation repair. Management of perforation is considered a challenging procedure especially when located in the furcation area, however histological evaluation of the tissue reaction to different internal matrices materials could provide favorable clinical outcomes concerning the perforation repair procedures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.