ReviewNature microbiology2025
How nutrient starvation impacts the gut microbiome.
Review in Nature microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Epigenetic legacies of famine: mechanistic pathways to obesity in modern environments.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Species-Specific Bacterial Associations Emerge From Stochastically Assembled Microbiomes in Northeastern American Fireflies.Molecular ecology · 2026Article
- Decoding the Gut-Fat-Heart Axis: From Molecular Communication Networks to Clinical Translation Strategies.International journal of molecular sciences · 2026Review
- Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Choline counteracts pregnancy undernutrition-associated colitis in sheep by restoring microbiota driven bile acid metabolism.NPJ biofilms and microbiomes · 2026Article
- Breakdown of microbial networks links nutrient stress and reef coral disease.Nature communications · 2026Article
- Genome-wide analysis exploring mechanisms used bymSystems · 2026Article
- Maltose aids in the growth ofFEMS microbes · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Even when the gut is rich in nutrients, microorganisms can experience nutrient deprivation owing to factors such as fluctuations in host feeding patterns, microbial competition and selective nutrient uptake by the host. Nutrient starvation affects microbial survival, microbiome dynamics and intestinal stability, yet remains underexplored. This Perspective explains how nutrient deprivation shapes microbial physiology, ecology and evolution to drive complex interactions both among microbial species and between microorganisms and their host. We discuss host lifestyles that can result in microbial starvation, including diet shifts, fasting and hibernation. We also highlight critical gaps in our understanding of how starvation affects microbial community assembly, stress responses and cross-feeding from lysed cells, with implications for chronic infections and therapeutic strategies. We outline technological developments needed to unravel microbial survival strategies under nutrient deprivation. Understanding how starvation in all its forms shapes the gut ecosystem will be important to ultimately advance microbiome engineering and health interventions.
Indexed as
Identifiers
41028229What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.