ReviewJournal of optometry
A review of contact lens discomfort: from the clinic to the laboratory.
Review in Journal of optometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Clinical Performance and Wearer Experience with Two Contemporary Daily Disposable Silicone Hydrogel Lenses.Clinical optometry · 2026Trial
- Misoprostol in Refractory Neuralgic Pain: From Clinical Neurology to an EP-Receptor Hypothesis of Pharmacodynamic Persistence.International journal of molecular sciences · 2026Review
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The exact mechanisms underlying contact lens discomfort (CLD) remain unknown. CLD results from reduced compatibility between the lens and the ocular environment, and multiple factors can trigger discomfort when wearing the lens. Consequently, this narrative review aims to elucidate the symptoms, clinical signs (singly and in combination) and ocular surface inflammatory mediators associated with CLD. This information could be useful for improving CLD management strategies in the future. A literature search of the PubMed database revealed widespread use of dry eye questionnaires in contact lens (CL) wearers, however, the emerging use of specific questionnaires for CLD is considered more appropriate. Besides, several inflammatory mediators might play a role in the development of CLD. Therefore, further studies are needed to investigate the role of ocular surface inflammatory mediators involved in CLD to better understand this condition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.