Evidence map›Paper›PMID 41027729›Full record

ArticleBMJ quality & safety2026

Digital quality measure of potentially avoidable emergency presentations among patients with colorectal cancer.

Natalia Khalaf, Basim Ali, Andrew Zimolzak, Yan Liu, Li Wei, Fasiha Kanwal, Hardeep Singh

Abstract read
In one paragraph

Article in BMJ quality & safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natalia KhalafCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA natalia.khalaf@bcm.edu.ORCID http://orcid.org/0000-0002-7585-6183
Basim AliSection of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Andrew ZimolzakCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.
Yan LiuCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.
Li WeiCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.
Fasiha KanwalCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.
Hardeep SinghCenter for Innovations in Quality, Effectiveness and Safety, Houston, Texas, USA.ORCID http://orcid.org/0000-0002-4419-8974

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
AHRQ HHS R01 HS028595AHRQ HHS R18 HS029347HSRD VA IK2 HX003346NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

backgroundWe previously developed a digital quality measure (dQM) of emergency presentations (EPs) in colorectal cancer (CRC) and found it to be associated with worse outcomes. Potentially avoidable EPs were common in this cohort, but identifying them required time-intensive chart reviews. We aimed to enhance the existing dQM to automate the detection of potentially avoidable EPs. MATERIALS AND

methodsWe defined potentially avoidable EPs as those preceded by a CRC red flag (iron-deficiency anaemia or haematochezia ≥60 days prior, or positive stool-based screening test ≥180 days prior). The enhanced dQM was applied to a national cohort of incident CRC cases diagnosed in the Veterans Affairs healthcare system from 2017 to 2021. We examined associations with cancer stage, treatment and mortality.

resultsThe enhanced dQM had a positive predictive value of 92% (95% CI 85.5% to 95.7%) for identifying potentially avoidable EPs. Among 9096 CRC cases, 28.1% were identified as EPs. Of these, 31.6% were classified as potentially avoidable. These patients were more likely to have advanced-stage disease (adjusted OR 1.50; 95% CI 1.27 to 1.78), less likely to receive treatment (adjusted OR 0.58; 95% CI 0.48 to 0.70) and had higher mortality (adjusted HR 1.58; 95% CI 1.40 to 1.79) compared with other patients with CRC.

conclusionsThe enhanced dQM accurately identified potentially avoidable EPs, which were associated with worse outcomes. This measure is unique in its focus on cases of preventable care delays, which can help guide future efforts to improve diagnostic timeliness and reduce EPs among patients with CRC.

Indexed as

Colorectal NeoplasmsEmergency Service, HospitalQuality Indicators, Health CareAgedFemaleHumansMaleMiddle AgedUnited StatesHealthcare quality improvementHealth services researchQuality measurement

Identifiers

PMID41027729
PMCPMC12629350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.