Evidence map›Paper›PMID 41027138›Full record

ArticleDevelopmental cognitive neuroscience2025

Previous institutionalization is associated with elevated functional connectivity between the nucleus accumbens and amygdala during aversive learning.

Benjamin M Rosenberg, João F Guassi Moreira, Adriana S Méndez Leal, Natalie M Saragosa-Harris, Elizabeth Gaines, Wesley J Meredith, Clare F McCann, Saché M Coury, Yael Waizman, Emilia Ninova and 1 more

Erratum issuedAbstract read
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In one paragraph

Article in Developmental cognitive neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Benjamin M RosenbergNeuroscience Department, Pomona College, Claremont, CA, USA. Electronic address: benjamin.rosenberg@pomona.edu.
João F Guassi MoreiraDepartment of Psychology, University of Wisconsin, Madison, WI, USA.
Adriana S Méndez LealDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Natalie M Saragosa-HarrisDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Elizabeth GainesDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Wesley J MeredithDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Clare F McCannDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Saché M CouryDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Yael WaizmanDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Emilia NinovaCollege of Social Work, Florida State University, Tallahassee, FL, USA.
Jennifer A SilversDepartment of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Funding

PREVENTION RESEARCH TRAINING:URBAN CHILDREN'S MENT HLTHT32MH015750 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTINE DUNKEL SCHETTER · 1985 to 2026
$6.2M
Doctoral Training in Brain and Behavioral Development During Adolescence (UCLA BBDA)T32HD091059 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Mirella Dapretto, ANDREW J FULIGNI · 2018 to 2026
$1.7M
NICHD NIH HHS T32 HD091059NIMH NIH HHS T32 MH015750
6 · The paper itself

Abstract

Institutionalization is a profound form of early adversity that is associated with increased risk for internalizing disorders, which most commonly have their onset during adolescence. Developmental models emphasize how differences in childhood learning contribute to avoidance behaviors, a core pathway linking adversity to internalizing disorders. Yet, little empirical research has tested this theory. 43 previously institutionalized (PI; 12.1-22.8 years) and 47 comparison (9.9-22.9 years) youth completed an aversive learning task while undergoing fMRI. The task involved an escapable stimulus reinforced with an aversive sound (CS+

Indexed as

AmygdalaAvoidance LearningChild, InstitutionalizedNucleus AccumbensAdolescentChildFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysReinforcement, PsychologyYoung AdultAdolescenceAnxietyDepressionEarly Life AdversityFunctional ConnectivityInstitutionalizationThreat Learning

Identifiers

PMID41027138
PMCPMC12513215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.