Evidence map›Paper›PMID 41027011›Full record

ArticleCritical care explorations2025

How High-Flow Nasal Cannula Is Impacted by Nasogastric/Esophageal Tube: A Bench Study.

Fernando Vieira, Annia Schreiber, Mayson L A Sousa, Rosie Butterworth, Shreyas Bhor, Antenor Rodrigues, Vorakamol Phoophiboon, Matthew Ko, Laurent Brochard

Abstract read
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Influence of leaks and mask design on COBMJ open respiratory research · 2026
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fernando VieiraCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.ORCID 0000-0001-9775-325
Annia SchreiberCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Mayson L A SousaCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Rosie ButterworthCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Shreyas BhorCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Antenor RodriguesCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Vorakamol PhoophiboonCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Matthew KoCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
Laurent BrochardCritical Care, Keenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.

Funding

Keenan Chair in Critical Care and Respiratory Failure
6 · The paper itself

Abstract

High-flow nasal cannula (HFNC) is a common noninvasive respiratory therapy for respiratory failure, offering positive airway pressure and dead space clearance. In critically ill patients, additional nasal tubes for feeding or monitoring are often required, but their effect on HFNC performance is not well understood. This bench study evaluated the impact of nasal tube placement on dead space clearance, nasopharyngeal pressure, and airway resistance using standard and asymmetrical cannulas. Inserting a 5-Fr tube with a standard cannula had very little effect, whereas bigger sizes (12-Fr and 16-Fr) slightly increased airway pressure and reduce Co2 clearance. An asymmetrical cannula exhibited variable effects depending on the side of the tube placement. Higher pressure and better clearance were achieved with a tube placed in the smaller cannula side. However, if occlusion of the two nares becomes excessive with the tube in place, downsizing the cannula might be recommended.

Indexed as

CannulaIntubation, GastrointestinalNoninvasive VentilationOxygen Inhalation TherapyRespiratory InsufficiencyAirway ResistanceEquipment DesignHumansgastric feeding tubeindwellingnasal cannularespiratory therapy

Identifiers

PMID41027011
PMCPMC12487933

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.