Evidence map›Paper›PMID 41026822›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The role of colony morphotype in shaping gene essentiality in

Brittany N Ross, Emma Evans, Frances Diggle, Paul Briaud, Marvin Whiteley

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Leucine auxotrophic marker for genetic manipulation ofApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Smooth-to-rough morphotype alterations inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Mycobacteriumabscessus CYP123 is a steroid hydroxylase with an implication in host infection.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brittany N RossCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.ORCID 0000-0002-9129-0693
Emma EvansCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.
Frances DiggleCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.
Paul BriaudCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.
Marvin WhiteleyCenter for Microbial Dynamics and Infection, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.ORCID 0000-0002-4933-9983

Funding

Probing Differences in Gene Essentiality Between Mycobacteroides abscessus Smooth and Rough Morphotypes During InfectionF32AI172296 · NIAID · GEORGIA INSTITUTE OF TECHNOLOGY · PI ROSS, BRITTANY N. · 2023 to 2024
$100k
Cystic Fibrosis Foundation (CFF) Ross20F0HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 1F32AI172296NIAID NIH HHS F32 AI172296
6 · The paper itself

Abstract

Changes in bacterial colony morphology are common during chronic human infections and are thought to provide a survival advantage. In the human pathogen

Indexed as

Genes, EssentialMycobacterium abscessusMycobacterium Infections, NontuberculousAnimalsDNA Transposable ElementsHumansMiceDNA Transposable Elementscystic fibrosisessential genesmorphotypeMycobacteroides abscessusTn-seq

Identifiers

PMID41026822
PMCPMC12519085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.