Evidence map›Paper›PMID 41026817›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Protopeptide backbone affects assembly in aqueous solutions.

Sarah Fisher, Yishi Ezerzer, Rotem Edri, Daniil Akulenko, Eliav Marland, Moran Frenkel-Pinter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah Fisher *Institute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.
Yishi Ezerzer *Institute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.
Rotem EdriInstitute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.
Daniil AkulenkoInstitute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.
Eliav MarlandInstitute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.
Moran Frenkel-PinterInstitute of Chemistry, The Hebrew University of Jerusalem, 9190401, Israel.ORCID 0000-0001-7235-5845

Funding

The Azrieli Foundation Early Career Grant N/AThe FEBS Foundation Excellence Award N/AThe Israel Science Foundation Grant 1611/22The Minerva Foundation N/A
6 · The paper itself

Abstract

One of the most fascinating mysteries in the field of origins of life concerns the driving force that led to the selection of today's 20 universal

Indexed as

DepsipeptidesPeptidesWaterAmino AcidsOrigin of LifeSolutionsAmino AcidsDepsipeptidesPeptidesSolutionsWaterchemical evolutiondepsipeptidesliquid-liquid phase separationorigins of lifeprebiotic chemistry

Identifiers

PMID41026817
PMCPMC12519194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.