Evidence map›Paper›PMID 41026782›Full record

ArticleeLife2025

Telomeres control human telomerase (

Antara Sengupta, Soujanya Vinayagamurthy, Dristhi Soni, Rajlekha Deb, Ananda Kishore Mukherjee, Subhajit Dutta, Jushta Jaiswal, Mukta Yadav, Shalu Sharma, Sulochana Bagri and 9 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Antara SenguptaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0000-0002-0974-9961
Soujanya VinayagamurthyIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0000-0003-1465-9925
Dristhi SoniIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Rajlekha DebIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Ananda Kishore MukherjeeIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Subhajit DuttaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0000-0003-2390-7492
Jushta JaiswalIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Mukta YadavIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Shalu SharmaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Sulochana BagriIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Shuvra Shekhar RoyIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0000-0001-6005-2767
Priya PooniaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Ankita SinghIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Divya KhannaIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.
Amit Kumar Kumar BhattIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0009-0002-8455-685X
Akshay SharmaLaboratory of Calciomics and Systemic Pathophysiology (LCSP), Regional Centre for Biotechnology (RCB), Faridabad, India.
Suman SauravLaboratory of Calciomics and Systemic Pathophysiology (LCSP), Regional Centre for Biotechnology (RCB), Faridabad, India.
Rajender K MotianiLaboratory of Calciomics and Systemic Pathophysiology (LCSP), Regional Centre for Biotechnology (RCB), Faridabad, India.ORCID https://orcid.org/0000-0002-8971-9008
Shantanu ChowdhuryIntegrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.ORCID https://orcid.org/0000-0001-7185-8408

Funding

Wellcome TrustWellcome Trust/DBT India Alliance IA/S/18/2/504021
6 · The paper itself

Abstract

The function of the human telomerase reverse transcriptase (referred hereafter as

Indexed as

TelomeraseTelomereTelomeric Repeat Binding Protein 2Cell Line, TumorHumansPromoter Regions, GeneticTelomeraseTelomeric Repeat Binding Protein 2TERF2 protein, humanTERT protein, humancancercancer biologychromosomesepigeneticsgene expressionhumantelomerasetelomereTRF2

Identifiers

PMID41026782
PMCPMC12483519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.