ArticleEnvironmental science & technology2025
Assessment of Population Relevance of Endocrine-sensitive Apical Endpoints in Fish Chronic Studies Using Individual-Based Models.
Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Population models have long been thought of as a suitable approach for assessing the population relevance of chemical effects observed on individuals in laboratory studies, although they have rarely been applied in a regulatory context. We modeled potential population-level responses of individual-level adverse effects induced by endocrine-disrupting chemicals (EDCs). We imposed three effect durations (10-year, 3 months summer, or winter) for six common EDC endpoints (fecundity, fertilization rate, sex ratio: male and female skew, courtship and nesting behavior) at four magnitudes of effect (10, 20, 50 and 90% reduction) using individual-based population models for three fish species with differing life histories: stickleback (
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