Evidence map›Paper›PMID 41026438›Full record

SynthesisJapanese journal of radiology2026

Percutaneous aspiration and sclerotherapy for simple hepatic cysts: a systematic review and meta-analysis.

Tomohiro Matsumoto, Rika Yoshimatsu, Marina Osaki, Junki Shibata, Kana Miyatake, Tomoaki Yamanishi, Takuji Yamagami

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tomohiro MatsumotoDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan. t-matsu@kochi-u.ac.jp.ORCID http://orcid.org/0000-0002-2375-4919
Rika YoshimatsuDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.
Marina OsakiDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.
Junki ShibataDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.
Kana MiyatakeDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.
Tomoaki YamanishiDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.
Takuji YamagamiDepartment of Diagnostic and Interventional Radiology, Kochi Medical School, Kochi University, Oko-cho, Kohasu, Nankoku, Kochi, 783-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review aims to assess the efficacy and safety of percutaneous aspiration and sclerotherapy (PAS) for patients with symptomatic simple hepatic cysts (SHCs). MATERIALS AND

methodsWe systematically searched the electronic databases of PubMed, Embase, the Cochrane Library and Ichushi-Web for studies published up to November 2024, reporting outcomes of PAS for symptomatic SHCs. The primary outcomes were rates of symptomatic relief or disappearance of symptoms. The secondary outcomes were cyst volume reduction rates and complication rates. Subgroup analyses compared ethanol with the other sclerosants. Single-arm meta-analyses were performed, with meta-regression conducted when substantial heterogeneity (I

resultsSixteen studies were included. Fourteen studies were assessed as having a high risk of bias. The pooled symptomatic relief or disappearance rate was 86.9% (95% CI 80.2-91.6%, I

conclusionPAS appears to be a relatively safe and effective treatment option for patients with symptomatic SHCs and provides high rates of symptomatic relief with low complication rates. However, given the high risk of bias in the available evidence and the lack of direct comparison with surgical treatment, these findings should be interpreted with caution. Further high-quality comparative studies are warranted to confirm these results.

Indexed as

CystsLiver DiseasesSclerotherapyHumansSclerosing SolutionsSuctionTreatment OutcomeSclerosing SolutionsInterventional radiologyMeta-analysisPercutaneous aspiration and sclerotherapySimple hepatic cyst

Identifiers

PMID41026438
PMCPMC12769637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.