Evidence map›Paper›PMID 41026404›Full record

ArticleJournal of endocrinological investigation2025

Impact of timing, type, and intensity of physical activity on glycemic outcomes in a cohort of well-controlled youth with type 1 diabetes.

Roberto Codella, Ambra Bisio, Marta Bassi, Nicola Minuto, Emilio Vichi, Daniel Gotti, Piero Ruggeri, Davide Maggi, Emanuela Faelli

Abstract read
In one paragraph

Article in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roberto CodellaDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, 20138, Italy. roberto.codella@unimi.it.ORCID http://orcid.org/0000-0003-1608-1899
Ambra BisioCentro Polifunzionale di Scienze Motorie, University of Genoa, Genoa, 16132, Italy.
Marta BassiPediatric Clinic, IRCCS Istituto Giannina Gaslini, University of Genoa, Genoa, Italy.
Nicola MinutoPediatric Clinic, IRCCS Istituto Giannina Gaslini, University of Genoa, Genoa, Italy.
Emilio VichiIRCCS San Martino, University of Genoa, Genoa, Italy.
Daniel GottiDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, 20133, Italy.
Piero RuggeriCentro Polifunzionale di Scienze Motorie, University of Genoa, Genoa, 16132, Italy.
Davide MaggiIRCCS San Martino, University of Genoa, Genoa, Italy.
Emanuela FaelliCentro Polifunzionale di Scienze Motorie, University of Genoa, Genoa, 16132, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate how the timing, type, and intensity of bout-related physical activity (PA) influence glycemic control across age groups in youths and young adults with type 1 diabetes (T1D). MATERIALS AND

methodsIn this cross-sectional study, 100 insulin pump-treated individuals with T1D (55 females; mean age 16.6 ± 6.6 years; HbA1c 6.8 ± 1.0%) were monitored for 7 days using self-reported training logs and continuous glucose monitoring. Participants were categorized by age (< 14, 14-17, 18-31 years) and by exercise timing (morning, afternoon, evening), type (aerobic, anaerobic, mixed), and intensity (low, medium, high). Glycemic variables included mean glucose, time in range (TIR), time below range (TBR), time in level 2 hypoglycemia, time above range (TAR), time > 250 mg/dL, and total daily insulin dose.

resultsExercise timing and intensity had greater effects on glycemic outcomes than exercise type. Afternoon activity was associated with improved TIR and reduced TAR in younger participants, whereas morning exercise in adolescents was linked to higher TBR. Higher-intensity exercise was associated with greater TAR in adolescents whereas no significant differences in glycemic outcomes were found by exercise type.

conclusionsThe timing and intensity of exercise significantly influence glycemic responses in youths with T1D, with notable age-related differences. Personalized PA recommendations should consider these factors to optimize glycemic outcomes.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 1ExerciseGlycemic ControlAdolescentAdultBlood Glucose Self-MonitoringChildCross-Sectional StudiesFemaleFollow-Up StudiesGlycated HemoglobinHumansHypoglycemiaHypoglycemic AgentsInsulinBlood GlucoseGlycated HemoglobinHypoglycemic AgentsInsulinCGMExerciseGlycemic controlPhysical activityType 1 diabetes

Identifiers

PMID41026404
PMCPMC12640312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.