Evidence map›Paper›PMID 41026382›Full record

ReviewJournal of community genetics2025

Genetic and genomic insights of the Comcáac people.

Alejandra Paulina Pérez-González, Israel Aguilar-Ordoñez, Norma A Caballero, Enrique Morett

Abstract readReview
In one paragraph

Review in Journal of community genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alejandra Paulina Pérez-GonzálezComputational Systems Biology/Integrative Genomics Laboratory, Instituto Nacional de Medicina Genómica, (INMEGEN), Ciudad de México, 14610, México.ORCID http://orcid.org/0000-0001-7352-4444
Israel Aguilar-OrdoñezTecnológico de Monterrey, OriGen Project, Monterrey, Nuevo León, México.ORCID http://orcid.org/0000-0002-6980-1151
Norma A CaballeroFacultad de Ciencias Biológicas, Benemérita Universidad Autónoma de Puebla, Heroica Puebla de Zaragoza, Puebla, 72592, México.ORCID http://orcid.org/0000-0002-9410-5852
Enrique MorettDepartamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, 62210, México. emorett@ibt.unam.mx.

Funding

CONAHCYT SNI Level III EXP.INV.8745Consejo Nacional de Humanidades, Ciencias y Tecnologías,Mexico 904078
6 · The paper itself

Abstract

The Comcáac (also known as Seri) are an indigenous community from the central coast of the Sonoran Desert in Mexico. Genetic studies conducted on this population since the late 1990s have revealed marked genetic differentiation resulting from pronounced genetic drift caused by a historical bottleneck, which is consistent with anthropological and linguistic records. Research has examined allele frequencies and genetic variants associated with cirrhosis risk, pathogen adaptation, forensic markers, vitamin and sugar metabolism, body mass index, immune responses, cytochrome genes, genetic distances with other groups, and migration patterns. While early investigations relied on classical genetic approaches, more recent studies have employed omics technologies, including whole-genome sequencing. Analyses of the Comcáac genome provide valuable insights into the phenotypic traits and medical predispositions of this community.

Indexed as

ComcáacGeneticsGenomicsIndigenousMolecular anthropologySeri

Identifiers

PMID41026382
PMCPMC12569335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.