Evidence map›Paper›PMID 41026226›Full record

ArticleNeuroradiology2025

Technical effectiveness and safety of emergent stenting in patients with acute ischemic stroke and carotid near-occlusion.

Andrés García Pastor, Isabel Lera Ramírez, Alejandro Bonilla Tena, David Seoane, Patricia Calleja, Fernando Ostos, Elena De Celis-Ruiz, Carlos Gómez Escalonilla, Patricia Simal, Alfonso López-Frías López-Jurado and 14 more

Abstract readClinical StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Andrés García PastorHospital General Universitario Gregorio Marañón, Madrid, Spain. agpastor@salud.madrid.org.
Isabel Lera RamírezHospital General Universitario Gregorio Marañón, Madrid, Spain.
Alejandro Bonilla TenaHospital General Universitario Gregorio Marañón, Madrid, Spain.
David SeoaneHospital Universitario 12 de Octubre, Madrid, Spain.
Patricia CallejaHospital Universitario 12 de Octubre, Madrid, Spain.
Fernando OstosHospital Universitario 12 de Octubre, Madrid, Spain.
Elena De Celis-RuizHospital Universitario La Paz, Madrid, Spain.
Carlos Gómez EscalonillaHospital Clínico San Carlos, Madrid, Spain.
Patricia SimalHospital Clínico San Carlos, Madrid, Spain.
Alfonso López-Frías López-JuradoHospital Clínico San Carlos, Madrid, Spain.
Daniel Perez GilHospital Universitario Ramón y Cajal, Madrid, Spain.
Rocío Vera LechugaHospital Universitario Ramón y Cajal, Madrid, Spain.
Cristina Moreno-LópezHospital Universitario Ramón y Cajal, Madrid, Spain.
Jose Carlos Fernandez-FerroHospital Universitario Rey Juan Carlos, Móstoles, Spain.
María Teresa Montalvo MoraledaHospital Universitario Rey Juan Carlos, Móstoles, Spain.
Javier Roa EscobarHospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Araceli García TorresHospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Inmaculada Navas VinagreHospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Eduardo Escolar EscamillaHospital Universitario de Getafe, Getafe, Spain.
Rodrigo Terrero CarpioHospital Universitario de Getafe, Getafe, Spain.
Guillermo Martín ÁvilaHospital Universitario de Getafe, Getafe, Spain.
Ana María Iglesias MohedanoHospital General Universitario Gregorio Marañón, Madrid, Spain.
Marta Vales MonteroHospital General Universitario Gregorio Marañón, Madrid, Spain.
Antonio Gil NúñezHospital General Universitario Gregorio Marañón, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increased very early risk (within the first 2 days after presenting event) of recurrent stroke among patients with symptomatic carotid near-occlusion (SCNO) and full collapse (FC) might justify ultra-early carotid revascularization of these patients. However, we lack data about technical effectiveness and safety of this approach in SCNO. This study aims to assess the feasibility and safety of emergent carotid stenting (eCAS) in patients with SCNO.

methodsMulticenter study including patients with acute stroke and extracranial carotid stenosis or occlusion undergoing mechanical thrombectomy and eCAS. The main outcomes were revascularization failure (incomplete carotid revascularization/occlusion at 48h), intracerebral hemorrhage (ICH) and symptomatic ICH (sICH). Patients with SCNO with and without FC were compared with the remaining patients.

results309 patients were included, 215 (69.6%) males, mean age (SD) 67.2 (12.8). 45 patients had SCNO and 16 SCNO + FC. Revascularization failure occurred in 15.6% of SCNO and in 13.4% of the remaining patients (p = 0.826), with no differences between SCNO with or without FC. ICH was more common in patients with SCNO (42% for all SCNO, 47% for SCNO + FC, and 24% for the remaining patients; p = 0.027). This increased risk of ICH associated with SCNO persisted in the multivariate analysis (OR 3.49 [95%CI 1.63 - 7.48], p = 0.001). No significant differences in the rate of sICH were observed between SCNO and the remaining patients.

conclusionsThe use of eCAS in acute SCNO seems to be feasible. However, the safety of the procedure is uncertain, as it could be associated with an increased risk of ICH.

Indexed as

Carotid StenosisIschemic StrokeStentsAgedFeasibility StudiesFemaleHumansMaleMiddle AgedThrombectomyTreatment OutcomeAcute ischemic strokeCarotid near-occlusionEmergent carotid artery stentingFull collapseIntracerebral hemorrhage

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.