Evidence map›Paper›PMID 41025624›Full record

ArticleFuture science OA2025

Rehabilitation intervention to prevent adverse events related to ADT in patients with metastatic prostate cancer.

Stefania Di Girolamo, Barbara Bressi, Cristina Masini, Stefania Fugazzaro, Stefania Costi, Monica Messori, Alessia Pecorari, Maria Beatrice Galavotti, Carlotta Sola, Claudia Ferrara and 5 more

Abstract read
In one paragraph

Article in Future science OA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stefania Di GirolamoMedical Oncology Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-5156-7400
Barbara BressiResearch and EBP Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-8014-2591
Cristina MasiniMedical Oncology Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0002-9926-8458
Stefania FugazzaroPhysical Medicine and Rehabilitation Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-6435-9504
Stefania CostiResearch and EBP Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0002-4645-0336
Monica MessoriResearch and EBP Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Alessia PecorariResearch and EBP Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0009-0008-1406-2313
Maria Beatrice GalavottiResearch and EBP Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Carlotta SolaPhysical Medicine and Rehabilitation Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Claudia FerraraPhysical Medicine and Rehabilitation Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Amelia AltavillaMedical Oncology Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0002-1598-9451
Giamaica CiardielloMedical Oncology Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Luca BragliaClinical Trial Center, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0001-8225-2938
Matteo AugugliaroRadiation Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Carmine PintoMedical Oncology Unit, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0002-3159-5268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with prostate cancer (PCa), androgen deprivation therapy (ADT) is associated with multiple side effects, including increased fat mass (FM), loss of muscle mass and strength, osteoporosis, risk of falls, disability, fatigue, and a decline in quality of life (QoL). Multicomponent exercise programs have been shown to mitigate several of these adverse events. Preliminary evidence suggests that exercise can be safely implemented in patients with metastatic PCa and that physical inactivity should be avoided, even in advanced stages. However, studies involving this fragile population remain limited. This single-arm interventional study aims to evaluate the feasibility and safety of an exercise-based rehabilitation program in hormone-sensitive patients undergoing ADT, alone or combined with other therapies.

Indexed as

adverse eventsandrogen-deprivation therapyexercisefeasibilitymetastatic prostate cancerrehabilitation

Identifiers

PMID41025624
PMCPMC12490355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.