ArticlePlant biotechnology journal2026
Alternaria alternata Effector Aa593 Promotes Virulence by Hijacking the CmNAC29-Mediated Abscisic Acid Biosynthesis Pathway in Chrysanthemum.
Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The interaction between plants and pathogens has long been an actively researched field of plant immunity. In this study, we found an Aa593/CmNAC29-CmNCED3 module associated with the interaction between chrysanthemum and the fungal pathogen Alternaria alternata. Here, we identified a transcription factor, CmNAC29, in chrysanthemum that promotes abscisic acid (ABA) biosynthesis by directly regulating CmNCED3, a key rate-limiting enzyme gene for ABA synthesis, thereby determining the susceptibility of plants to A. alternata. On invading plants, pathogens secrete effectors that contribute to regulating plant immune responses. Interestingly, we screened a novel effector, Aa593, secreted by A. alternata that targets CmNAC29 in the plant cell nucleus. By interacting with CmNAC29 and thus enhancing its transcriptional activation activity, Aa593 promotes ABA biosynthesis and subsequently weakens plant resistance to A. alternata. Furthermore, genetic transformation assays indicated Aa593 contributes to the virulence of A. alternata. Our findings in this study have enabled us to elucidate how fungal effectors target plant hormone signalling pathways to promote their virulence and lay the theoretical foundations for further studies on the pathogenic mechanism of necrotrophic fungi.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.