Evidence map›Paper›PMID 41025254›Full record

ReviewJournal of clinical laboratory analysis2025

Nanomaterial-Enhanced Electrochemical Sensors for Clinical Monitoring of Acyclovir: Integration Into Molecular Diagnostics.

Mohammad Darvishi, Mohammad Mahdi Heidari, Reza Kheradmand, Nava Moghadasian Niaki, Mahsa Tabean, Ahmad Mobed

Abstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammad DarvishiInfectious Disease, School of Aerospace and Subaquatic Medicine, Infectious Diseases & Tropical Medicine Research Center(IDTMC), AJA University of Medical Sciences, Tehran, Iran.
Mohammad Mahdi HeidariDepartment of Pediatrics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Reza KheradmandSocial Determinants of Health Research Center, Health Management and Safety Promotion, Tabriz, Iran.
Nava Moghadasian NiakiWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mahsa TabeanWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad MobedSocial Determinants of Health Research Center, Health Management and Safety Promotion, Tabriz, Iran.

Funding

Tabriz University of Medical Sciences
6 · The paper itself

Abstract

objectiveThis study investigates the innovative application of nanomaterial-based micro-devices aimed at enhancing the diagnosis and management of acyclovir (ACV) for herpes virus infections, specifically those caused by HSV-1, HSV-2, CMV, and VZV.

backgroundHerpes viruses are associated with various clinical diseases, highlighting the urgent need for effective antiviral therapies. Acyclovir remains a primary treatment option; however, its potential for kidney toxicity and allergic reactions necessitates careful dosage monitoring, particularly in immunocompromised patients.

methodsRecent advancements in drug monitoring systems have been developed to optimize dosing regimens and reduce the risk of misuse. This study focuses on the integration of biological and electrochemical nanosensors utilizing nanomaterials, which have shown significant improvements in detection capabilities and diagnostic sensitivity for ACV.

resultsWe delineate the novel features and applications of these micro-devices, emphasizing their unique configurations and unprecedented limits of detection.

conclusionThis research illustrates how these advanced technologies can enhance existing methodologies in herpes virus management, ultimately leading to improved treatment outcomes.

Indexed as

AcyclovirAntiviral AgentsBiosensing TechniquesDrug MonitoringElectrochemical TechniquesHerpesviridae InfectionsNanostructuresHumansPathology, MolecularAcyclovirAntiviral Agentsacyclovirbiosensorelectrochemical sensorsnanomaterial‐based sensorpharmaceutical drug

Identifiers

PMID41025254
PMCPMC12572734

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.