Evidence map›Paper›PMID 41025158›Full record

ArticleThe veterinary quarterly2025

Development and immunogenicity of adenoviral Fc-fused FMDV virus-like particle vaccine in swine.

Jae-Yeon Park, Hye-Mi Lee, Ki-Jong Kang, Min Kyo Jung, Ji Young Mun, Moon-Ju Kim, Jae-Cheol Pyun, Seong Yun Hwang, Jong-Hyeon Park, Hyun-Jin Shin

Abstract read
In one paragraph

Article in The veterinary quarterly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jae-Yeon ParkCollege of Veterinary Medicine, Chungnam National University, Daejeon, S. Korea.
Hye-Mi LeeCollege of Veterinary Medicine, Chungnam National University, Daejeon, S. Korea.
Ki-Jong KangCollege of Veterinary Medicine, Chungnam National University, Daejeon, S. Korea.
Min Kyo JungNeural Circuit Research Group, Korea Brain Research Institute, Daegu, S. Korea.
Ji Young MunNeural Circuit Research Group, Korea Brain Research Institute, Daegu, S. Korea.
Moon-Ju KimDepartment of Materials Science and Engineering, Yonsei University, Seoul, S. Korea.
Jae-Cheol PyunDepartment of Materials Science and Engineering, Yonsei University, Seoul, S. Korea.
Seong Yun HwangCenter for FMD Vaccine Research, Animal and Plant Quarantine Agency, Gimcheon, S. Korea.
Jong-Hyeon ParkCenter for FMD Vaccine Research, Animal and Plant Quarantine Agency, Gimcheon, S. Korea.
Hyun-Jin ShinCollege of Veterinary Medicine, Chungnam National University, Daejeon, S. Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-mouth disease (FMD) remains a major threat to global livestock health, and current inactivated vaccines face limitations in biosafety and cross-protection. Virus-like particle (VLP) -based vaccines offer a safer alternative, however, their production is often hindered by the cytotoxicity of the viral 3C protease. In this study, we developed a modified 3C protease with reduced cytotoxicity, enabling efficient expression of FMDV VLPs

Indexed as

Foot-and-Mouth DiseaseFoot-and-Mouth Disease VirusImmunogenicity, VaccineSwine DiseasesVaccines, Virus-Like ParticleViral VaccinesAdenoviridaeAnimalsAntibodies, NeutralizingAntibodies, ViralCapsid ProteinsImmunoglobulin Fc FragmentsSwineAntibodies, NeutralizingAntibodies, ViralCapsid ProteinsImmunoglobulin Fc FragmentsVaccines, Virus-Like ParticleViral VaccinesadenoviruscytokineFMD vaccineFMDV VLP-sFcFoot and mouth disease virus (FMDV)immune responseneutralizing antibodyvirus-like particles (VLPs)

Identifiers

PMID41025158
PMCPMC12486460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.