Evidence map›Paper›PMID 41025149›Full record

ArticleJournal of medicinal chemistry2025

Synthesis of Phosphonate Derivatives of Benzisoselenazolones and Their Remarkable Antiureolytic Activity in

Marta Grabarek, Wojciech Tabor, Paweł Krzyżek, Julia Bąkowicz, Agnieszka Grabowiecka, Łukasz Berlicki, Artur Mucha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marta GrabarekDepartment of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Wojciech TaborDepartment of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-3682-2765
Paweł KrzyżekDepartment of Microbiology, Faculty of Medicine, Wrocław Medical University, Chałubińskiego 4, 50-368 Wrocław, Poland.
Julia BąkowiczInstitute of Advanced Materials, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Agnieszka GrabowieckaDepartment of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-5825-0702
Łukasz BerlickiDepartment of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0003-0318-4944
Artur MuchaDepartment of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.ORCID 0000-0002-6421-1371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The attachment of a nickel-ion-complexing functionality to the structures of covalent inhibitors of ureases has been considered an effective method for enhancing binding to these pivotal virulence factors of various microbial pathogens. Following this approach, we envisioned a structural combination of 1,2-benzisoselenazol-3(2

Indexed as

Anti-Bacterial AgentsHelicobacter pyloriOrganophosphonatesOrganoselenium CompoundsUreaseMicrobial Sensitivity TestsSporosarcinaStructure-Activity RelationshipAnti-Bacterial AgentsOrganophosphonatesOrganoselenium CompoundsUrease

Identifiers

PMID41025149
PMCPMC12516687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.