Evidence map›Paper›PMID 41025093›Full record

ArticleWorld journal of virology2025

Hepatitis C virus-associated cardiomyopathy: A review of pathogenesis.

Inderjeet Singh Bharaj, Gurkaranvir Singh, Ajit Singh Brar, Aayushi Kacheria, Jasraj Kahlon, Billal Mohmand, Aalam Sohal, Beeletsega T Yeneneh

Abstract read
In one paragraph

Article in World journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026
    Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Inderjeet Singh BharajDepartment of Internal Medicine, Abrazo Health Network, Glendale, AZ 85308, United States.
Gurkaranvir SinghDepartment of Internal Medicine, Creighton University School of Medicine, Phoenix, AZ 85012, United States.
Ajit Singh BrarDepartment of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI 48503, United States.
Aayushi KacheriaDepartment of Internal Medicine, Abrazo Health Network, Glendale, AZ 85308, United States.
Jasraj KahlonDepartment of Internal Medicine, Abrazo Health Network, Glendale, AZ 85308, United States.
Billal MohmandDepartment of Cardiology, University of Arizona Banner University Medical Center, Phoenix, AZ 85006, United States.
Aalam SohalDepartment of Gastroenterology and Hepatology, Creighton University School of Medicine, Phoenix, AZ 85012, United States. aalamsohal@gmail.com.
Beeletsega T YenenehDepartment of Cardiology, University of Arizona Banner University Medical Center, Phoenix, AZ 85006, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis C virus (HCV) affects millions of individuals globally and is linked to dilated cardiomyopathy and hypertrophic cardiomyopathy

aimTo review the pathogenesis of cardiomyopathy in patients infected with HCV and investigate its clinical implications.

methodsA narrative literature review (PubMed, Scopus, Google Scholar; 1990-2024) focused on English-language studies examining the HCV-cardiomyopathy link, pathophysiology, and treatment. The findings were qualitatively synthesized.

resultsHCV drives cardiomyopathy through direct viral toxicity, immune damage, genetic factors, and apoptosis. The associated cirrhosis contributes

conclusionHCV is a significant cardiomyopathy risk factor involving diverse pathways, including cirrhosis. DAA therapy offers cardiovascular benefits. Further research on the underlying mechanisms, biomarkers (

Indexed as

CardiomyopathyCardiotropicCirrhosisDirect-acting antiviralsHepatitis C virus

Identifiers

PMID41025093
PMCPMC12476814

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.