ArticleWorld journal of cardiology2025
Systematic review and meta-analysis: Is surgical cardiac denervation effective against postoperative atrial fibrillation?
Article in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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15 authors.
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Abstract
backgroundPostoperative atrial fibrillation (POAF) is a complication after cardiac surgeries associated with increased morbidity and hospital stay. Surgical cardiac denervation, which reduces autonomic input to the heart, has been proposed as a good preventive against POAF. However, evidence on its effectiveness remains inconsistent.
aimTo evaluate the impact of surgical cardiac denervation on the incidence of POAF and related clinical outcomes.
methodsThis meta-analysis adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A literature search was conducted across PubMed, Cochrane, ScienceDirect, and EMBASE up to April 2025 using a preformed search strategy using Medical Subject Headings terms and free-text keywords. Risk of bias assessment was done
resultsFive studies (
conclusionSurgical cardiac denervation does not significantly reduce overall POAF but does lower the incidence of persistent atrial fibrillation. It is also shown to decrease serum magnesium levels. Other outcomes, such as stroke, reoperation, and hospital stay, showed no significant differences.
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