Evidence map›Paper›PMID 41024966›Full record

ArticleWorld journal of cardiology2025

Optical coherence tomography-guided percutaneous coronary intervention compared to angiography-guided percutaneous coronary intervention for complex lesions.

Muhammad Burhan, Humza Saeed, Muhammad Usama, Aamnah Tariq, Saira Shafiq, Sonia Hurjkaliani, Minahil Iqbal, Sufyan Shahid, Salman Khalid, Naeem Khan Tahirkheli

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muhammad BurhanDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi 87500, Punjab, Pakistan.
Humza SaeedDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi 87500, Punjab, Pakistan. hamzasaeed309@gmail.com.
Muhammad UsamaDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi 87500, Punjab, Pakistan.
Aamnah TariqDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi 87500, Punjab, Pakistan.
Saira ShafiqDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi 87500, Punjab, Pakistan.
Sonia HurjkalianiDepartment of Internal Medicine, Dow University of Health Sciences, Karachi 74200, Sindh, Pakistan.
Minahil IqbalDepartment of Internal Medicine, Allama Iqbal Medical College, Lahore 54000, Punjab, Pakistan.
Sufyan ShahidDepartment of Internal Medicine, Khawaja Muhammad Safdar Medical College, Sialkot City 51300, Punjab, Pakistan.
Salman KhalidDepartment of Cardiology, Oklahoma Heart Hospital, Oklahoma City, OK 73120, United States.
Naeem Khan TahirkheliDepartment of Cardiology, Oklahoma Heart Hospital, Oklahoma City, OK 73120, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOptical coherence tomography (OCT) offers detailed cross-sectional imaging during percutaneous coronary intervention (PCI), aiding in anatomically complex coronary lesions. Despite its advantages, evidence on the clinical effectiveness of OCT-guided PCI remains limited.

aimTo compare clinical outcomes of OCT-guided

methodsMajor databases were systematically searched for randomized controlled trials (RCTs) comparing OCT-guided and angiography-guided PCI in complex lesions. Primary outcomes included major adverse cardiovascular events (MACE) and target vessel failure (TVF); secondary outcomes included mortality, myocardial infarction (MI), and other procedural outcomes. A random-effects model was used to pool risk ratio (RR), with 95%CI. Statistical analysis was conducted in R software (v4.4.1), with significance set at

resultsFive RCTs (5737 patients) showed OCT-guided PCI significantly reduced MACE (RR: 0.63, 95%CI: 0.52-0.77,

conclusionOCT-guided PCI improves outcomes in complex lesions by reducing MACE, TVF, mortality, stent thrombosis, and target-vessel MI. These findings highlight the need for further large-scale RCTs to confirm its benefits.

Indexed as

AngiographyComplex lesionIntravascular imagingMajor adverse cardiovascular eventMeta-analysisOptical coherence tomographyPercutaneous coronary intervention

Identifiers

PMID41024966
PMCPMC12476618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.