ArticleWorld journal of nephrology2025
Automated peritoneal dialysis with shortened break-in periods in urgent-start scenarios: A retrospective cohort study.
Article in World journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundEnd-stage kidney disease is a growing global health burden with many patients requiring urgent kidney replacement therapy. Urgent-start peritoneal dialysis (PD) has emerged as a viable alternative to hemodialysis particularly in resource-limited settings. However, concerns remain regarding catheter-related complications associated with early initiation of PD. Automated PD (APD) offers enhanced flexibility and fluid management, but evidence regarding its safety and outcomes in urgent-start scenarios with shortened break-in periods is limited.
aimTo evaluate the clinical outcomes and biochemical changes associated with urgent-start APD with a shortened break-in period.
methodsThis was a single center, observational study that included 62 patients with end-stage kidney disease who required urgent-start dialysis, underwent PD catheter placement, and received APD. Patients were stratified based on catheter opening time (< 12 hours
resultsThe median catheter opening time was 11 h (interquartile range: 8-14 hours). No significant differences in catheter-related complications were observed between groups (
conclusionUrgent-start APD with shortened break-in appears safe with low complication rates and improved biochemical outcomes.
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