Evidence map›Paper›PMID 41024855›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Association Between Sedentary Lifestyle, Physical Activity, and Skin Cancer Among Outpatient US Adults: Evidence from NHANES.

Ze-Qun Qiu, Shan-Yuan Ye, Run-Dong Zhang, Meng Cao, Yan Wang

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ze-Qun QiuHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Shan-Yuan YeHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Run-Dong ZhangHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Meng CaoHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.
Yan WangHospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sedentary behavior has been identified as a potential risk factor for various malignancies, whereas physical activity serves as a protective factor for certain cancers. The aim of this study was to explore the associations between these two factors and the prevalence of melanoma and non-melanoma skin cancers (NMSCs). Methods: We collected cross-sectional data from 26,731 participants in the NHANES from 2007 to 2016. Multivariate logistic regression and subgroup analyses were used to assess the correlations between sedentary behavior, physical activity, and the prevalence of melanoma and NMSCs. Results: Multivariable logistic regression indicated that sedentary behavior was not significantly associated with melanoma or NMSCs. The type and score of physical activity were not related to melanoma (p > 0.05). However, moderate-intensity physical activity (including both work and recreation activities) and physical activity scores in the 2001-4000 range were positively correlated with NMSCs. Subgroup analysis and interaction tests showed no significant differences in NMSC prevalence between participants with a physical activity score ranging from 2001-4000, suggesting that gender, Poverty Income Ratio (PIR), and education level were not significantly related to this positive correlation (p < 0.05). However, after adjusting for UV radiation as a covariate, the logistic regression results of the NMSCs were no longer significant. Conclusion: Our study results indicate that, for individuals aged 20 and above in the US, SB is not associated with the prevalence of melanoma or NMSCs. There is no significant correlation between physical activity and the prevalence of melanoma, but a positive correlation exists with NMSCs'. However, this association was attenuated and lost statistical significance after adjustment for sunburn history as a proxy for UV exposure. We need more prospective and well-designed studies to validate our findings to promote early prevention and lifestyle interventions for high-risk populations of NMSCs.

Indexed as

melanomanon-melanoma skin cancerphysical activitypublic healthsedentary behavior

Identifiers

PMID41024855
PMCPMC12476851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.