Evidence map›Paper›PMID 41024849›Full record

ArticleWorld journal of clinical oncology2025

Synchronous cholangiocarcinoma and cervical squamous cell carcinoma managed

Zhi-Jian Wu, Bin Wang, Si-Cong Zhao, Zhan-Teng Pan

Abstract readCase Reports
In one paragraph

Article in World journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhi-Jian WuDepartment of Hepatobiliary Surgery, Dongyang People's Hospital, Affiliated to Wenzhou Medical University, Dongyang 322100, Zhejiang Province, China. zhijian.wu.med@qq.com.
Bin WangDepartment of Hepatobiliary Surgery, Dongyang People's Hospital, Affiliated to Wenzhou Medical University, Dongyang 322100, Zhejiang Province, China.
Si-Cong ZhaoDepartment of Hepatobiliary Surgery, Dongyang People's Hospital, Affiliated to Wenzhou Medical University, Dongyang 322100, Zhejiang Province, China.
Zhan-Teng PanDepartment of Hepatobiliary Surgery, Dongyang People's Hospital, Affiliated to Wenzhou Medical University, Dongyang 322100, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple primary cancers refer to the presence of two or more distinct malignant tumors in a single individual, either simultaneously or sequentially. The synchronous occurrence of cholangiocarcinoma (CCA) and cervical squamous cell carcinoma (SCC) is extremely rare. This case highlights the diagnostic challenges and significance of a multidisciplinary team in managing complex malignancies involving both the hepatobiliary and gynecologic systems. The 8 CASE SUMMARY: A 74-year-old postmenopausal woman (Karnofsky performance status = 80) presented with a one-day history of vaginal bleeding. Cross-sectional imaging (contrast-enhanced computed tomography, liver magnetic resonance imaging, and positron emission tomography/computed tomography) first demonstrated a single 3-cm lesion in liver segment V and a hypermetabolic cervical mass. Subsequent ultrasound-guided liver biopsy confirmed CCA, whereas cervical biopsy revealed SCC. After multidisciplinary discussion, the patient underwent laparoscopic liver resection. Pelvic external-beam radiotherapy was delivered at 45 grays in 25 fractions (6-megavolt photons) over 5 weeks, followed by high-dose-rate

conclusionMultidisciplinary management offers a promising strategy for treating synchronous complex malignancies with individualized treatment plans.

Indexed as

Case reportCervical squamous cell carcinomaCholangiocarcinomaImmunotherapyLiver resectionMultiple primary neoplasmsRadiotherapy

Identifiers

PMID41024849
PMCPMC12476617

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.