ArticleNeurogastroenterology and motility2025
Epidemiology of Meal-Related Abdominal Discomfort or Pain in Irritable Bowel Syndrome.
Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dietary Therapies for Gastrointestinal Disorders.Nutrients · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with IBS often report meal-related symptoms, which may negatively affect IBS-related quality of life, psychological health, and lead to food-avoidant behaviors. However, the understanding of the epidemiology of these symptoms is limited.
methodsWe compared characteristics of adult patients with Rome IV-defined IBS with and without meal-related abdominal discomfort or pain ≥ 50% of the time. Participants were recruited from the ContactME-IBS research register. We collected data concerning demographics, IBS symptoms, psychological health, quality of life, and impact on work and daily activities using validated questionnaires. We used logistic regression to explore independent predictors of meal-related discomfort or pain ≥ 50% of the time in IBS. KEY
resultsOf 752 respondents with Rome IV IBS, 561 (74.6%) reported meal-related abdominal discomfort or pain ≥ 50% of the time. 89.3% of individuals with meal-related discomfort or pain ≥ 50% of the time were female vs. 80.6% of those without (p = 0.002). Those with meal-related discomfort or pain ≥ 50% of the time were younger (43.7 years vs. 50.1 years, p < 0.001), had a higher prevalence of symptoms meeting criteria for functional dyspepsia (FD), especially postprandial distress syndrome (49.1% vs. 30.2%, p < 0.001), and reported higher gastrointestinal symptom-specific anxiety scores, lower IBS-related quality of life scores, and higher levels of activity impairment (p < 0.001 for all analyses). After logistic regression analysis, females, those meeting criteria for FD, younger individuals, and those reporting higher gastrointestinal symptom-specific anxiety scores were more likely to report meal-related discomfort or pain ≥ 50% of the time.
conclusionsMeal-related abdominal discomfort or pain ≥ 50% of the time was associated with female sex, younger age, and comorbid FD. Better characterization and recognition of patients affected by meal-related discomfort or pain may allow more personalized dietary and psychological interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.