Evidence map›Paper›PMID 41024637›Full record

ArticleACS sensors2025

Spectrally Silent and Optically Transparent: Clear-SiR for Deep Raman Biomolecular Sensing.

Michael Ka Ho Lee, Kenta Mizushima, Peng Zheng, Swati Tanwar, Anoushka Gupta, Katsumasa Fujita, Ishan Barman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS sensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael Ka Ho LeeDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Kenta MizushimaDepartment of Applied Physics, Osaka University, Suita, Osaka 565-0871, Japan.
Peng ZhengDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0001-5907-8505
Swati TanwarDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0002-0430-1922
Anoushka GuptaDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Katsumasa FujitaDepartment of Applied Physics, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0002-2284-375X
Ishan BarmanDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0003-0800-0825

Funding

Next-generation optical nanoprobes: From quantum biosensing to cellular monitoringR35GM149272 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ISHAN BARMAN · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM149272
6 · The paper itself

Abstract

Raman spectroscopy (RS) offers highly specific, label-free molecular identification, yet its application in deep-tissue imaging is fundamentally limited by light scattering and spectral interference from endogenous biomolecules. A promising strategy to mitigate these issues involves using vibrational tags that emit signals within the Raman-silent region (1800-2800 cm

Indexed as

Spectrum Analysis, RamanAnimalsHumansMiceRefractometrydeep-tissue sensingraman spectroscopytartrazinetissue clearingvibrational tags

Identifiers

PMID41024637
PMCPMC12993836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.