Evidence map›Paper›PMID 41024613›Full record

ReviewCancer biology & medicine2025

Current progress in neoantigen-based dendritic cell vaccines for solid tumors.

Yuting Li, Abudukadierjiang Abudureheman, Jianming Xu

Abstract readReview
In one paragraph

Review in Cancer biology & medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuting Li *Department of Oncology, The First Medical Center, Chinese PLA General Hospital/Medical School of Chinese PLA, Beijing 100853, China.
Abudukadierjiang Abudureheman *Department of Oncology, The First Medical Center, Chinese PLA General Hospital/Medical School of Chinese PLA, Beijing 100853, China.
Jianming XuDepartment of Oncology, The Fifth Medical Center of the PLA General Hospital, Beijing 100071, China.ORCID 0000-0003-4467-6021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy, particularly immune checkpoint inhibitors (ICIs) programmed death-ligand 1/programmed death-1 (PD-L1/PD-1) and cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4), has heralded a new era of tumor treatment. Although ICIs have clinical benefits, their complex heterogeneity and diverse resistance mechanisms critically limit their efficacy. Neoantigens, arising from tumor-specific alterations, offer novel targets for individualized immunotherapy, because of their high immunogenicity and tumor specificity. In the past decade, neoantigen-based tumor vaccines have been demonstrated to be a promising immunotherapy strategy to prime the tumor-specific immune response. These therapeutic vaccines include peptide vaccines, nucleic acid vaccines, and dendritic cell (DC) vaccines, and are categorized according to the neoantigen source and delivery method.

Indexed as

Antigens, NeoplasmCancer VaccinesDendritic CellsNeoplasmsAnimalsHumansImmunotherapyAntigens, NeoplasmCancer Vaccinesdendritic cellimmunotherapyNeoantigensolid tumorvaccines

Identifiers

PMID41024613
PMCPMC12533755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.