Evidence map›Paper›PMID 41024592›Full record

ArticleMagnetic resonance in medicine2026

Optimized 3D UTE and ZTE MRI for high-resolution lung imaging: A comparative study.

Michael Carl, Jiaji Wang, James Lo, Jonathan H Chung, Jiang Du, Yajun Ma

Abstract readComparative Study
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael CarlGE Healthcare, San Diego, California, USA.
Jiaji WangDepartment of Radiology, University of California San Diego, San Diego, California, USA.
James LoDepartment of Radiology, University of California San Diego, San Diego, California, USA.ORCID 0000-0002-7351-0752
Jonathan H ChungDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Jiang DuDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Yajun MaDepartment of Radiology, University of California San Diego, San Diego, California, USA.ORCID 0000-0003-0830-9232

Funding

Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Quantitative UTE MR Imaging of Myelin: Novel Biomarkers for Alzheimer's DiseaseRF1AG075717 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2022 to 2022
$2.3M
CSRD VA I01 CX002211GE HealthcareNIAMS NIH HHS R01 AR079484NIA NIH HHS RF1 AG075717NIH HHS R01AR079484NIH HHS RF1AG075717Veterans Affairs Clinical Science Research and Development I01CX002211
6 · The paper itself

Abstract

purposeTo optimize and compare the performance of 3D UTE and zero echo time (ZTE) MRI sequences for high-resolution lung imaging at 3 T.

methodsUTE and ZTE sequences were optimized for lung imaging through phantom studies, and in vivo experiments. Imaging parameters, including bandwidth (BW) and flip angle (FA), were systematically assessed to identify the optimal settings for both sequences. A novel transient UTE sequence was introduced to enhance the SNR by allowing magnetization recovery during the respiratory wait period. Numerical simulations and in vivo experiments were conducted to compare the SNR performance of the proposed transient UTE with conventional steady-state UTE.

resultsUTE imaging with a BW of ±125 kHz and an FA of 2° produced the sharpest lung images without noticeable artifacts. In contrast, ZTE imaging was optimal at a lower BW of ±62.5 kHz and an FA of 2°, but showed greater blurriness and more pronounced inhomogeneous excitation artifacts than UTE. The transient UTE sequence increased lung imaging SNR by approximately 11% to 20% compared to steady-state UTE without introducing obvious artifacts.

conclusionUTE outperformed ZTE in terms of image sharpness and artifact reduction for lung imaging. The proposed transient UTE sequence further enhanced SNR, demonstrating the potential for improved lung MRI quality and diagnostic accuracy.

Indexed as

Imaging, Three-DimensionalLungMagnetic Resonance ImagingAlgorithmsAnimalsArtifactsComputer SimulationHumansImage Processing, Computer-AssistedPhantoms, ImagingReproducibility of ResultsSignal-To-Noise Ratiolungsteady‐statetransientUTEZTE

Identifiers

PMID41024592
PMCPMC12790902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.