Evidence map›Paper›PMID 41024478›Full record

ArticleMagnetic resonance in medicine2026

Optimized T

Oliver Bieri, Marcel Dominik Nickel, Claudia Weidensteiner, Philipp Madörin, Grzegorz Bauman

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimized TMagnetic resonance in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oliver BieriDepartment of Biomedical Engineering, University of Basel, Allschwil, Switzerland.ORCID https://orcid.org/0000-0002-6755-5495
Marcel Dominik NickelResearch & Clinical Translation, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.
Claudia WeidensteinerDepartment of Biomedical Engineering, University of Basel, Allschwil, Switzerland.
Philipp MadörinDepartment of Biomedical Engineering, University of Basel, Allschwil, Switzerland.
Grzegorz BaumanDepartment of Biomedical Engineering, University of Basel, Allschwil, Switzerland.ORCID https://orcid.org/0000-0001-6972-0776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo propose and evaluate an optimized MP-RAGE protocol for rapid T

methodsIncoherent and coherent steady state free precession (SSFP) RAGE kernels with constant and variable excitation angles were investigated in terms of the white matter SNR and the white matter-gray matter signal difference. Potential edge smearing from the transient signal readout was assessed based on a differential point spread function analysis. Finally, the prospects of a deep-learning reconstruction (DLR) method for accelerated MP-RAGE MRI of undersampled data were evaluated for the best performing variant.

resultsMP-RAGE imaging with a variable flip angle (vFA) SSFP-FID kernel outperformed all other investigated variants. As compared to the standard MPRAGE sequence using a spoiled gradient echo kernel with constant flip angle, vFA SSFP-FID offered an average gain in the white matter SNR of 21% ± 2% and an average improvement for the white matter-gray matter signal difference for cortical gray matter of 47% ± 7%. The differential point spread function was narrowest for the spoiled gradient echo but slightly increased by 8% for vFA SSFP-FID. For vFA SSFP-FID, DLR offered a considerable decrease in the overall scan time from 5:17 min down to 2:46 min without noticeable image artifacts and degradations.

conclusionsAt 0.55 T, a vFA MP-RAGE variant using an SSFP-FID kernel combined with a DLR method offers excellent prospects for rapid T

Indexed as

BrainDeep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingAdultAlgorithmsFemaleGray MatterHumansImage Interpretation, Computer-AssistedMaleSignal-To-Noise RatioWhite Matterdeep learning reconstructionimage enhancementlow‐fieldMP‐RAGEMRIT1‐weighted brain

Identifiers

PMID41024478
PMCPMC12681286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.