Evidence map›Paper›PMID 41024377›Full record

ArticleEuropean journal of haematology2026

Complications in Central Venous Access Devices in Paediatric Cancer Care: A Global Cross-Sectional Survey.

Sabrina de Souza, Mari D Takashima, Areum Hyun, Victoria Gibson, Thiago Lopes Silva, Patricia Kuerten Rocha, Siriporn Vetcho, Sophie C H Wen, Amanda J Ullman

Abstract read
In one paragraph

Article in European journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Central venous access device-associated complication costs in paediatric cancer care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabrina de SouzaSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-3628-0134
Mari D TakashimaSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0002-1167-9106
Areum HyunSchool of Nursing and Midwifery, Griffith University, Nathan, Queensland, Australia.
Victoria GibsonSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.
Thiago Lopes SilvaPostgraduate Program in Nursing, Universidade Federal de Santa Catarina, Florianopolis, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0002-6310-5825
Patricia Kuerten RochaPostgraduate Program in Nursing, Universidade Federal de Santa Catarina, Florianopolis, Santa Catarina, Brazil.ORCID https://orcid.org/0000-0002-8347-1363
Siriporn VetchoFaculty of Nursing, Prince of Songkla University, Songkhla, Thailand.
Sophie C H WenQueensland Children's Hospital, Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland, Australia.
Amanda J UllmanSchool of Nursing, Midwifery and Social Work, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, Queensland, Australia.ORCID https://orcid.org/0000-0001-8860-5319

Funding

Cancer Council QueenslandUniversity of Queensland ACCR-118
6 · The paper itself

Abstract

objectiveTo examine global practices for identifying and managing central venous access device (CVAD) complications-catheter-associated bloodstream infection (CABSI), thrombosis, and occlusion-in paediatric cancer care, comparing patterns between high- and other-income countries.

methodsA cross-sectional international survey was conducted from 2022 to 2023 and analysed 2024 to 2025. Clinicians involved in paediatric CVAD cancer care were recruited through global networks.

resultsA total of 161 respondents from 38 countries completed the complication section, including 102 (63.4%) from high-income and 59 (36.6%) from other-income countries (lower- and upper-middle income). For CABSI, blood culture was the main diagnostic method (122 [75.8%]; high-income: 87 [85.3%], other-income: 35 [59.3%]). Differential time to positivity was more often reported in other-income settings (33 [55.9%] vs. 35 [34.3%]), who also more frequently initiated antibiotics based on nonspecific or immediate criteria. CABSI treatment varied, with intravenous antibiotics (68 [60.7%]) and catheter removal (47 [42.0%]) most reported. For thrombosis, anticoagulation before line removal was common (88 [54.7%]), and alteplase use was higher in high-income countries (76 [74.5%] vs. 19 [32.2%]). Thrombolytic agents were the most reported treatment for occlusion (103 [64.0%]), especially in high-income countries (77 [75.5%] vs. 26 [44.1%]).

conclusionsCVAD complication management varies by country income level, highlighting the need for context-adapted guidelines, training, and equitable access to key resources.

Indexed as

Catheterization, Central VenousCatheter-Related InfectionsCentral Venous CathetersNeoplasmsChildCross-Sectional StudiesHumansSurveys and QuestionnairesThrombosiscentral venous catheterschildren patient safetycross‐sectional studieshospitaloncology servicevascular access devices

Identifiers

PMID41024377
PMCPMC13460855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.