Evidence map›Paper›PMID 41024222›Full record

ArticleBehavioral and brain functions : BBF2025

Representation of top-down versus bottom-up attention in the right dorsolateral prefrontal cortex and superior parietal lobule.

Qiuzhu Zhang, Wenjuan Li, Tingting Zhang, Ronglong Xiong, Junjun Zhang, Zhenlan Jin, Ling Li

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In one paragraph

Article in Behavioral and brain functions : BBF, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Qiuzhu ZhangMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Wenjuan LiMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Tingting ZhangMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Ronglong XiongMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Junjun ZhangMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Zhenlan JinMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
Ling LiMOE Key Lab for Neuroinformation, Brain-Computer Interface & Brain-Inspired Intelligence Key Laboratory of Sichuan Province, Center for Psychiatry and Psychology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China. liling@uestc.edu.cn.

Funding

National Natural Science Foundation of China 62176045Sichuan Province Innovative Talent Funding Project for Postdoctoral Fellows BX202402Sichuan Science and Technology Program 2025ZNSFSC0453
6 · The paper itself

Abstract

backgroundVisual selective attention can be categorized into top-down (goal-driven) and bottom-up (stimulus-driven) attention, with the fronto-parietal network serving as the primary neural substrate. However, fewer studies have focused on the specific roles of the right dorsolateral prefrontal cortex (DLPFC) and superior parietal lobule (SPL) in top-down and bottom-up attention. This study aimed to investigate the activity and connectivity of the right DLPFC and SPL in top-down and bottom-up attention.

methodsVisual pop-out task mainly induces bottom-up attention, while the visual search task mainly induces top-down attention. Fifty-four participants completed the pop-out and search tasks during functional magnetic resonance imaging (fMRI) scanning. We used univariate analyses, multivariate pattern analyses (MVPA), and generalized psychophysiological interaction (gPPI) to assess activity and functional connectivity.

resultsUnivariate analyses revealed stronger activation in the right DLPFC and SPL during the search > pop-out condition. The activation of the DLPFC was driven by its deactivation in the pop-out task, whereas the SPL showed significant activation in both tasks. MVPA demonstrated that activation patterns in the right DLPFC and SPL could distinguish between the pop-out and search tasks above chance level (0.5), with the right SPL exhibiting higher classification accuracy. The gPPI analyses showed that higher functional connectivity between the two seeds (right DLPFC and SPL) and bilateral precentral gyrus, left SPL, and right insula.

conclusionsThese results indicate that the right DLPFC and SPL showed stronger activity and connectivity under top-down versus bottom-up attention, allowing for neural representation of visual selective attention. This study provides evidence for understanding the role of the fronto-parietal network in visual selective attention.

Indexed as

AttentionDorsolateral Prefrontal CortexParietal LobePrefrontal CortexAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysPhotic StimulationVisual PerceptionYoung AdultBottom-up attentionFunctional magnetic resonance imaging (fMRI)Right dorsolateral prefrontal cortex (DLPFC)Right superior parietal lobule (SPL)Top-down attention

Identifiers

PMID41024222
PMCPMC12482898

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.