Evidence map›Paper›PMID 41024210›Full record

ReviewJournal of health, population, and nutrition2025

Cholera in Nigeria: a five-decade review of outbreak dynamics and health system responses.

Tolulope Joseph Ogunniyi, Amaka Perpetual Muoneke, Faith Nimo, Sarah Sokolabe Yisa, Oluwaloseyi Ayomipo Olorunfemi

Abstract readReview
In one paragraph

Review in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tolulope Joseph OgunniyiDepartment of Medical Microbiology and Parasitology, State Specialist Hospital Damaturru, Damaturu, Yobe State, Nigeria. josephtolulopeogunniyi@gmail.com.
Amaka Perpetual MuonekeDepartment of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, College of Medicine, University of Nigeria, Enugu campus (UNEC), Nsukka, Enugu State, Nigeria.
Faith NimoDepartment of Medical Parasitology and Entomology, University of Calabar, Calabar, Cross River State, Nigeria.
Sarah Sokolabe YisaDepartment of Hematology and Blood Transfusion Science, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
Oluwaloseyi Ayomipo OlorunfemiDepartment of Chemical Pathology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCholera remains a significant public health concern in Nigeria, with recurrent outbreaks over the past five decades. Despite advancements in healthcare, the country continues to record high case fatality rates, largely due to inadequate water, sanitation, and hygiene (WASH) infrastructure, poor health systems, climate variability, and conflict-induced displacement.

objectiveThis review aimed to examine the historical trends of cholera in Nigeria, identify key drivers of outbreaks, evaluate government and international responses, and recommend strategic measures for prevention and control.

methodsA comprehensive analysis was conducted using historical outbreak data, peer-reviewed literature, and reports from national and international health agencies. The study focuses on outbreaks from 1970 to 2024, highlighting epidemiological trends, response strategies, and systemic challenges.

resultsCholera has persisted as an endemic disease in Nigeria, with major outbreaks recorded in 1991, 2010, and 2021. Case fatality rates often exceeded the World Health Organization's (WHO) recommended threshold of < 1%, indicating systemic deficiencies in outbreak response and healthcare delivery. Contributing factors include poor sanitation, limited access to clean water, underfunded healthcare infrastructure, and weak surveillance systems. Climate change and population displacement due to conflict have further exacerbated the risk of transmission.

conclusionNigeria's approach to cholera control remains reactive, with limited progress in sustainable prevention. Multi-sectoral strategies including improved WASH infrastructure, enhanced surveillance, local vaccine production, and community-based interventions are essential to achieving the WHO 2030 cholera elimination goals.

Indexed as

CholeraDelivery of Health CareDisease OutbreaksHumansHygieneNigeriaPublic HealthSanitationCholeraClimate changeEpidemiologyNigeriaPublic health

Identifiers

PMID41024210
PMCPMC12482021

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.