Evidence map›Paper›PMID 41024206›Full record

ArticleJournal of health, population, and nutrition2025

Association of dietary acid load with abdominal adiposity based on traditional and novel anthropometric indices.

Niloufar Abdollahpour, Farima Farsi, Glareh Koochackpoor, Hossein Hatamzadeh, Habibollah Esmaily, Mahdieh Zarif Sadeghian, Gordon A Ferns, Najmeh Seifi, Majid Ghayour-Mobarhan

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Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Niloufar AbdollahpourDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 9177948564, Iran.
Farima FarsiObesity and Eating Habits Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Glareh KoochackpoorSchool of Nursing and Allied Medical Sciences, Maragheh University of Medical Sciences, Maragheh, Iran.
Hossein HatamzadehDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 9177948564, Iran.
Habibollah EsmailyDepartment of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahdieh Zarif SadeghianEndoscopic and Minimally Invasive Surgery research center, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon A FernsDivision of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, UK.
Najmeh Seifi *Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 9177948564, Iran. seifin@mums.ac.ir.
Majid Ghayour-Mobarhan *Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 9177948564, Iran. ghayourm@mums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral or visceral adiposity is associated with metabolic syndrome and related health problems. The association of dietary acid load (DAL) with body mass index (BMI) and waist circumference (WC) has been studied in a few previous studies. We aimed to investigate the association of dietary acidity with abdominal obesity which was assessed using traditional and more novel indices.

methodsIn this cross-sectional study, a total of 6482 participants aged 35-65 years were recruited as part of the MASHAD cohort study. Dietary intakes were assessed using a validated food frequency questionnaire. Dietary acid load was assessed as the potential renal acid load (PRAL), net endogenous acid production (NEAP), and DAL. Central obesity was defined as a WC ≥ 94 cm in men and 80 cm in women, waist-hip ratio (WHR) ≥ 0.9 in men, and 0.85 in women, and body shape index (ABSI) and abdominal volume index (AVI) above the median. Multivariable logistic regression models were applied to determine the association between diet-based acid load scores and abdominal obesity.

resultsIn the crude and age-adjusted models for women, higher levels of NEAP were related to an increased risk of central obesity, as measured by WC and WHR. For women, NEAP was associated with an increased odds of central obesity based on ABSI in the full-adjusted model (odds ratios (ORs) and 95% confidence intervals (CIs): 1.234 (1.045-1.456)). In both gender groups, higher levels of DAL were related to increased chances of central obesity based on WC, WHR and AVI across all models. However, the multiple logistic regression ORs and 95% CIs for abdominal adiposity indices across levels of PRAL showed no significant association in the fully adjusted model.

conclusionOur findings suggest that a higher dietary acid measured by NEAP and DAL load may contribute to an increased risk of abdominal obesity. Notably, this effect appears to be more pronounced in women.

Indexed as

AcidsDietObesity, AbdominalAdiposityAdultAgedAnthropometryBody Mass IndexCohort StudiesCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedRisk FactorsAcidsABSIAVICentral obesityDietary acid loadWC

Identifiers

PMID41024206
PMCPMC12482787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.