Trial reportEuropean journal of medical research2025
Preoperative carbohydrate fluid intake reduces postoperative nausea and vomiting without increasing gastric volume in neuroendoscopic sellar tumor surgery.
Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The Effect of Intravenous Dextrose Administration on Postoperative Nausea and Vomiting: Systematic Review and Meta-Analysis with Trial Sequential Analysis.Medicina (Kaunas, Lithuania) · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluated the effect of preoperative carbohydrate fluid intake on gastric volume (GV), blood glucose (BG), reflux aspiration, and postoperative nausea and vomiting (PONV) in patients with sellar tumors undergoing neuroendoscopic transnasal-sphenoidal sinus resection (NTSR).
methodsFifty-eight patients scheduled for elective NTSR were randomly assigned to Group A (n = 29), who received 400 mL of 10% glucose solution orally 2 h before anesthesia, or Group B (n = 29), who fasted for at least 8 h. Gastric ultrasound was used to measure antral diameters before induction and after surgery, from which GV was estimated. BG levels were recorded at fasting (T1), before induction (T2), and after surgery (T3). The incidence of PONV within 24 h, reflux aspiration, and hospital stay duration were also assessed.
resultsIn Group A, the mean GV decreased significantly from 47.81 ± 2.45 mL before induction to 45.71 ± 2.08 mL after surgery (p < 0.05), while no significant change was observed in Group B. Before induction, GV was higher in Group A than in Group B (p < 0.05). No patients experienced reflux aspiration in either group. The incidence of PONV was significantly lower in Group A (23.1%, 6/26) than in Group B (65.4%, 17/26; p < 0.05). BG levels at all time points showed no significant intergroup differences.
conclusionsCarbohydrate fluids taken 2 h before anesthesia do not increase GV or aspiration risk but reduce PONV in NTSR patients without affecting BG levels.
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