Evidence map›Paper›PMID 41024165›Full record

ReviewJournal of cannabis research2025

Enhancing Methods for Research on Cannabis: A Workshop Report.

Jonathan M Samet, Jessica Barrington-Trimis, Lisa Bero, Ashley Brooks-Russell, Meghan Buran, Julia Dilley, Darin Erickson, Marilyn Huestis, Kent Hutchison, Thomas L Jeanne and 10 more

Abstract readReview
In one paragraph

Review in Journal of cannabis research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jonathan M SametColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA. Jon.Samet@cuanschutz.edu.
Jessica Barrington-TrimisUniversity of Southern California, Los Angeles, USA.
Lisa BeroUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, USA.
Ashley Brooks-RussellColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA.
Meghan BuranColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA.
Julia DilleyOregon Health Authority, Salem, USA.
Darin EricksonUniversity of Minnesota, Minneapolis, USA.
Marilyn HuestisThomas Jefferson University, Philadelphia, USA.
Kent HutchisonUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, USA.
Thomas L JeanneOregon Health Authority, Salem, USA.
Michael KosnettColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA.
David J KrollUniversity of Colorado School of Pharmacy, Anschutz Medical Campus, Aurora, USA.
Stephen LankenauDrexel University, Philadelphia, USA.
Richard MiechUniversity of Michigan, Ann Arbor, USA.
Rosalie Liccardo PaculaUniversity of Southern California, Los Angeles, USA.
Paula RiggsUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, USA.
Neeloofar SoleimanpourColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA.
Steven TeutschUniversity of Southern California, Los Angeles, USA.
Gregory TungColorado School of Public Health, 13001 E. 17th Place, Aurora, CO, 80045, USA.
George Sam WangUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsProgressive legalization of medical and recreational cannabis markets at the state-level has led to rapid growth of medical and recreational cannabis markets and to product diversification with emerging products having high concentrations of delta-9-tetrahydrocannabinol. Research on these products is still limited and the evidence available for policy formulation is diminished by methodological limitations.

methodsAs a step towards addressing these limitations, the Colorado School of Public Health convened a multidisciplinary workshop that addressed four areas of cannabis research: epidemiological, clinical, surveillance, and policy. Workshop participants provided recommendations in each area to advance research on cannabis to make it more informative for decision-making on key policy topics. Emphasis was placed on assessment of use of cannabis products by study participants.

resultsRecommendations for research methods and their implementation were made in the four areas. Those for epidemiology include using a core set of exposure assessment measures across three domains; developing this core set through a national and/or international scientific consensus process; ensuring the core set of measures are validated and readily available; and updating the core set periodically to account for ongoing changes in the cannabis landscape. Recommendations in the clinical research area include standard dosing and dosing terminology; standardized data collection instruments; identifying biomarkers for detecting cannabis exposure; and biological matrices. Policy research recommendations were offered for state regulators, evaluators/researchers, and policy makers. Surveillance recommendations include developing and implementing a novel and nimble surveillance system to monitor use of high-concentration forms of cannabis; adding questions to existing surveillance systems with the objective of monitoring high-concentration cannabis and adverse outcomes; and elevating the coordination, synthesis, and dissemination of findings in existing data sources that could signal adverse outcomes from high-concentration cannabis.

conclusionsGiven the changing marketplace, it is urgent to improve the informativeness of cannabis research through enhanced research methods.

Indexed as

Clinical researchDelta-9-tetrahydrocannabinolDoseEpidemiological researchExposureHigh-concentration cannabisPolicyPublic healthSurveillance

Identifiers

PMID41024165
PMCPMC12482547

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.