Evidence map›Paper›PMID 41024089›Full record

SynthesisBMC women's health2025

Prevalence and correlates of female sexual dysfunction and sexual distress in reproductive-aged women: a systematic review and meta-analysis.

Fatemeh Heshmatnia, Marzieh Azizi, Hamed Milani, Roya Nikbakht, Mohsen Kheiri, Hadis Tolomehr, Zohreh Shahhosseini

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Impact of the pandemic on sexual function: A comparative study between women of reproductive age and postmenopausal women.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Observational
  5. Article
  6. Article
  7. Article
  8. Effects of Shatavari (International journal of women's health · 2026
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatemeh HeshmatniaDepartment of Nursing and Midwifery, Islamic Azad University, Se.C, Semnan, Iran.
Marzieh AziziDepartment of Midwifery, Sexual and Reproductive Health Research Center, Mazandaran University of Medical Sciences, Sari, Iran. marziehazizi70@gmail.com.
Hamed MilaniSchool of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Roya NikbakhtDepartment of Biostatics and Epidemiology, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Mohsen KheiriStudent Research Committee, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Hadis TolomehrStudent Research Committee, School of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, Iran.
Zohreh ShahhosseiniDepartment of Midwifery, Sexual and Reproductive Health Research Center, Mazandaran University of Medical Sciences, Sari, Iran. zshahhosseini@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemale sexual dysfunction (FSD) is defined as any dissatisfaction with sexual function domains such as sexual desire/arousal disorder, orgasmic disorders, and genital-pelvic pain/penetration disorder that in some cases leads to sexual distress (SD).

objectiveThis systematic review and meta-analysis aimed to examine the prevalence and associated factors of FSD and SD among healthy reproductive-aged women.

methodsIn this systematic review and meta-analysis, Google Scholar and electronic databases such as Scopus, ScienceDirect, PubMed, Web of Science, and the Iranian database including the Scientific Information Database (SID), were searched and the publication year of the included articles were limited to January 1, 2015, through January 1, 2024 to identify studies that assessed FSD and SD among reproductive-aged women. The quality of the included studies was evaluated using the Newcastle-Ottawa Scale for cross-sectional and cohort studies.

resultsTwenty studies were included in this review. According to the results of 18 studies, the prevalence of FSD ranged between 20.6% and 95.0%. In addition, the prevalence of sexual desire disorder (SDD) was estimated between 8.0% and 91.0% based on the results of 16 studies. The prevalence of arousal disorder (9.0-91.0%), orgasm disorder (7.9-93.0%), lubrication problems (9.3-99.0%), pain disorder (8.2-99.0%), and satisfaction (21.4-86.0%). SD prevalence was 31.8-83.4%. Meta-analysis revealed a pooled FSD prevalence of 47.81% (95% CI: 39.19-56.43%). The factors related to FSD were classified into five main categories: sociodemographic, reproduction, interpersonal, psychological, and medical factors. Also, the associated factors of SD were classified into four categories: sociodemographic, interpersonal, psychological, and medical factors. The risk of bias for all of the included studies was good.

conclusionThe results of this study showed that reproductive-aged women are at high risk of FSD and SD due to various factors. As the literature regarding SD among the reproductive-aged population was limited, conducting high-quality cross-sectional studies with representative samples and using validated questionnaires are required to provide more precise data regarding its prevalence and associated factors across diverse cultural contexts.

trial registrationPROSPERO; Registration no. CRD42024491942.

Indexed as

Sexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalAdultCross-Sectional StudiesFemaleHumansPrevalenceFemale sexual dysfunctionPrevalenceReproductive-agedRisk factorsSexual distress

Identifiers

PMID41024089
PMCPMC12481727

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.