Trial reportBMC cancer2025
Combined effects of slow movement training with tonic force generation and aerobic exercise prior to cancer therapy in patients with lung cancer (START-lung): a pilot feasibility trial.
Trial report in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Should supportive care be started before initiating cancer treatment?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundExercise is known to improve physical fitness, functional performance, muscle strength, quality of life (QoL), and treatment outcomes in patients with cancer. However, the feasibility and impact of implementing an exercise program from the first visit for suspected advanced lung cancer to treatment initiation remain unclear. This study aimed to evaluate the feasibility of a structured exercise program during this period.
methodsThis prospective, single-center study included patients with suspected advanced lung cancer who were instructed to perform a pre-treatment 4-week exercise program consisting of slow movement training with tonic force generation and aerobic exercise. Attendance rates and adverse events were assessed, and changes in functional performance, exercise capacity, balance function, muscle strength and mass, physical activity levels, nutritional status, and QoL were evaluated. Patient feedback on the exercise program was collected.
resultsA total of 17 patients were analyzed, with a mean age of 70 years. The overall exercise attendance rate was 159.7 ± 54.4%. A high attendance rate (≥70.8%) was achieved by 15 patients without any adverse events. Significant improvements from baseline to after-exercise intervention were observed in the five-time sit-to-stand test and 30-second chair stand test. No significant changes in 6-minute walk distance, one-leg standing time, isometric handgrip and knee extensor strengths, skeletal muscle mass or self-reported measures were observed. Patient feedback indicated that exercise was beneficial in alleviating anxiety and maintaining physical condition during the waiting period before treatment.
conclusionsA structured exercise program initiated from the first visit to treatment initiation was feasible and safe in patients with advanced lung cancer. Notably, improvements in the five-time sit-to-stand test and 30-second chair stand test were observed, suggesting potential benefits for enhancing lower-limb functional performance during this period. Further studies, including randomized controlled trials, are warranted to assess its impact on clinical outcomes and long-term patient wellbeing.
trial registrationUniversity Hospital Medical Information Network, UMIN000055155. Date of registration: August 5, 2024
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.