Evidence map›Paper›PMID 41023898›Full record

ArticleBMC cardiovascular disorders2025

The mortality of ischemic heart disease attributable to temperature variability: findings from the Global Burden of Disease Study 2021.

Anheng Liu, Jiaman Lin, Hongyu Ma, Qiang Wang

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Anheng Liu *Department of Cardiology, Beijing Jingmei Group General Hospital, Beijing, 102300, China.
Jiaman Lin *Chinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Beijing, 100071, China.
Hongyu Ma *Department of Cardiology, Beijing Jingmei Group General Hospital, Beijing, 102300, China.
Qiang WangChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Beijing, 100071, China. wang76qiang@163.com.

Funding

Beijing Natural Science Foundation 7242192National Natural Science Foundation of China 81973003
6 · The paper itself

Abstract

objectiveTo investigate the effect of temperature variability on ischemic heart disease (IHD) mortality and to provide a scientific basis for disease prevention and control strategies.

methodsAge-standardized mortality rates (ASMRs) for temperature-related IHD were extracted from the Global Burden of Disease 2021 database. Joinpoint regression was used to analyze the trend of the ASMRs. Age-period-cohort (APC) models were used to analyze independent age, period and cohort effects. Bayesian APC model was used to project ASMRs into the next 30 years.

resultsFrom 1990 to 2021, ASMR of IHD related to low temperature decreased with time. However, ASMR related to high temperature demonstrated a gradual increase, though was still lower than ASMR related to low temperature. ASMR was higher in males than in females. Age, period and cohort effects were dominant in the risk of death related to temperature. Low temperature associated ASMR was higher in high and high-middle socio-demographic index (SDI) regions, but declined more rapidly than other SDI regions over time. Except for high SDI regions, high temperatures in other regions tended to increase ASMR. Pakistan, Montenegro and Lesotho were the countries with the largest increases in ASMR related to low temperatures. The largest increases in ASMR related to high temperatures were observed in Egypt, Iraq and Saudi Arabia. Projections indicated that the risk of high temperature-induced mortality would continue to increase over time.

conclusionsIHD deaths associated with temperature variability are heterogeneous, with low temperature leading to a decreased risk of death and high temperature being a significant factor contributing to the continued increase in mortality risk.

Indexed as

Cold TemperatureHot TemperatureMyocardial IschemiaAdultAgedAge DistributionAge FactorsDatabases, FactualFemaleGlobal Burden of DiseaseGlobal HealthHumansMaleMiddle AgedRisk AssessmentRisk FactorsHigh temperatureIschemic heart diseaseLow temperatureMortalityTemperature variability

Identifiers

PMID41023898
PMCPMC12482138

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