Evidence map›Paper›PMID 41023892›Full record

ArticleBMC medical imaging2025

Sound touch viscosity in the evaluation of median nerve in healthy volunteers-a preliminary study.

Jun Huang, Hongpeng Duan, Minwei Zhang, Jian Lu, Feng Mao, Ling Zhou, Shengmin Zhang

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Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Jun Huang *Department of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Hongpeng Duan *Department of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Minwei ZhangDepartment of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Jian LuDepartment of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Feng MaoDepartment of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Ling ZhouDepartment of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China.
Shengmin ZhangDepartment of Medical Ultrasound, The First Affiliated Hospital of Ningbo University, No.59 LiuTing Street, Ningbo, 315010, China. fyyzhangshengmin@nbu.edu.cn.

Funding

General Program of the Medical and Health Science and Technology Plan of Zhejiang Province 2023KY1077Innovation Fund of the National High-Performance Medical Device Innovation Center FAHNBU 20240475the Public Welfare Science and Technology Program of Ningbo City 2024S144
6 · The paper itself

Abstract

backgroundQuantitative assessment of peripheral nerve viscoelasticity is important for understanding nerve physiology and detecting early neuropathic changes. However, reference values for the viscosity and stiffness of the median nerve in healthy adults are lacking. MATERIALS AND

methodsA total of 98 healthy volunteers (58 females, 40 males; mean age: 35 ± 12 years) were assessed using the Sound Touch Viscosity and shear wave elastography modules integrated into the Resona A20S ultrasound system. Viscosity and stiffness were measured at three anatomical locations: the carpal tunnel (MN1), mid-forearm (MN2), and 5 cm proximal to the elbow joint (MN3). Paired bilateral measurements were obtained, and demographic factors were analyzed for their influence.

resultsNo significant differences were found between the left and right median nerves (p > 0.05). MN1 showed the highest viscosity 1.83 Pa·s (1.48-2.13) and stiffness of 30.24 kPa (28.46-33.65) significantly greater than MN2 and MN3 (p < 0.001). Viscosity and stiffness were moderately correlated at all sites ((r = 0.39, 0.56, and 0.36; all p < 0.001). Males showed higher stiffness at all locations (p < 0.001) and higher viscosity at MN1 and MN2 (p = 0.039 and 0.011). While age and body mass index (BMI) showed no significant effects.

conclusionSTVi is a feasible and reproducible modality for quantifying median nerve viscoelasticity. Viscoelastic parameters vary significantly by anatomical location and sex, with no influence from age and BMI. These findings establish normative values and support the clinical applicability of Sound Touch Viscosity in peripheral nerve assessment.

Indexed as

Elasticity Imaging TechniquesMedian NerveTouchAdultFemaleHealthy VolunteersHumansMaleMiddle AgedReference ValuesSoundViscosityYoung AdultHealthy volunteersMedian nerveShear wave elastographyUltrasoundViscosity

Identifiers

PMID41023892
PMCPMC12482535

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