Evidence map›Paper›PMID 41023879›Full record

ArticleBMC gastroenterology2025

Treatment of patients with hyperthyroidism and liver failure: a retrospective cohort study.

Zhanyi Li, Xiangyong Li, Xiaoqiong Shao, Qinyao Xu, Yuankai Wu, Yu Liu

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Mechanisms and Prognostic Assessment Value of Thyroid Hormone in Liver Failure.Journal of clinical and translational hepatology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhanyi Li *Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Xiangyong Li *Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Xiaoqiong ShaoDepartment of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Qinyao XuDepartment of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China.
Yuankai WuDepartment of Infectious Diseases, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China. wuykai@mail.sysu.edu.cn.
Yu LiuDepartment of Thyroid and Breast Surgery, The Third Affiliated Hospital of Sun Yat-sen University, 600 Tianhe Road, Tianhe District, Guangzhou, Guangdong, 510630, China. liuyu67@mail.sysu.edu.cn.

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515110818Guangzhou Science and Technology Project 202201020453
6 · The paper itself

Abstract

backgroundHyperthyroidism complicated by liver failure is associated with high mortality, and the optimal treatment strategy remains unclear. We aimed to compare the clinical characteristics of patients who received different treatments for hyperthyroidism and liver failure.

methodsThis retrospective cohort study included 137 patients diagnosed with hyperthyroidism and Liver failure between January 2013 and December 2022. The patients were treated with methimazole (MMI) plus artificial liver support system (ALSS), radioactive iodine (

resultsAfter propensity score matching, no significant differences in treatment efficacy were observed between MMI plus ALSS and MMI alone at discharge (P = 0.425), 12 weeks (P = 0.104), or 24 weeks (P = 0.104). There were also no significant differences in treatment efficacy between

conclusionsOur results suggest that

Indexed as

Antithyroid AgentsHyperthyroidismIodine RadioisotopesLiver, ArtificialLiver FailureMethimazoleAdultAgedCombined Modality TherapyFemaleHumansLength of StayMaleMiddle AgedPropensity ScoreRetrospective StudiesAntithyroid AgentsIodine RadioisotopesMethimazoleAntithyroid drugsArtificial liver support systemHyperthyroidismLiver failureRadioactive iodineTreatment efficacy

Identifiers

PMID41023879
PMCPMC12482396

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.