ArticleBMC geriatrics2025
New indicators related to the osteosarcopenia in the elderly: assessment of intrinsic capacity.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The interplay between osteosarcopenia and intrinsic capacity: insights and associations with all-cause mortality in the Toledo Study for Healthy Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile intrinsic capacity (IC) has been associated with reduced sarcopenia risk, its relationship with osteosarcopenia remains unexplored. This study aimed to elucidate the association between IC and osteosarcopenia in older adults.
methodsThis cross-sectional study enrolled outpatient patients ≥ 60 years to investigate IC-osteosarcopenia associations. IC was quantified through a multidimensional score integrating cognition, mobility, vitality, psychological, and sensory domains. Osteosarcopenia was defined as concurrent osteoporosis and sarcopenia. Participants underwent stratification based on osteoporosis/sarcopenia comorbidity status. Multivariable-adjusted logistic models assessed IC-osteosarcopenia risk gradients, with subgroup analyses exploring age/sex-specific effects and comorbidity interactions.
resultsIn this cohort of 461 older adults (median age 80 years), osteosarcopenia prevalence reached 26%. Logistic regression analysis identified: cognitive [odds ratio (OR): 0.871, 95% confidence interval (CI): 0.808–0.933] and sensory (OR: 0.633, 95% CI: 0.417–0.950) impairments specifically predicted osteosarcopenia, while vitality deficits demonstrated dual risks for both sarcopenia (OR: 0.820, 95% CI: 0.725–0.920) and osteosarcopenia (OR: 0.736, 95% CI: 0.648–0.826). Locomotor impairment and psychological distress emerged as pan-risk factors across sarcopenia, osteoporosis, and osteosarcopenia. Total IC scores exhibited dose-dependent associations with all three musculoskeletal outcomes (P < 0.05), maintaining significance across age/sex subgroups and after confounding variables adjustment.
conclusionTotal IC score serves as a significant predictor of osteosarcopenia in elderly patients. Cognition, mobility, vitality, psychological, and sensory domains were associated with osteosarcopenia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.