ArticleBMC cardiovascular disorders2025
Sex differences in neurological outcomes for patients with In-Hospital cardiac arrest.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundSex differences in cardiac arrest outcomes had been widely studied in out-of-hospital cardiac arrest (OHCA). However, limited research has explored the impact of sex on neurological outcomes of patients with in-hospital cardiac arrest (IHCA).
objectiveThis study aimed to investigate the association between sex and neurological outcomes at hospital discharge in IHCA patients.
methodsA retrospective cohort study analyzed 1,536 adult IHCA patients from National Taiwan University Hospital. Neurological outcomes were categorized as favorable (CPC 1-2) or poor (CPC 3-5). Propensity score matching and logistic regression adjusted for confounders, with sensitivity and subgroup analyses validating results.
resultsThe female had significantly poorer neurological outcomes compared to the male (95.34% vs. 90.80%, P < 0.001). Female sex was independently associated with poor neurological outcomes across multiple analytical approaches. In the unadjusted analysis, female patients demonstrated significantly higher odds of poor neurological outcomes (OR = 2.07, 95%CI: 1.34-3.22, P = 0.001). This association persisted after adjusting for clinical variables (Model 1: OR = 2.38, 95%CI: 1.40-4.03, P = 0.001) and propensity scores (Model 2: OR = 2.38, 95%CI: 1.39-4.01, P < 0.001). In the propensity score-matched cohort (n = 1,180), the association strengthened, with the fully adjusted model showing the robust relationship (Model 3: OR = 2.77, 95%CI: 1.54-4.99, P < 0.002). Sensitivity and subgroup analyses consistently supported these findings.
conclusionFemale was independently associated with poor neurological outcomes in IHCA patients. The findings highlighted the need for further research to explore underlying mechanisms and develop sex-specific strategies to improve IHCA outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.