Evidence map›Paper›PMID 41023760›Full record

ArticleArthritis research & therapy2025

Sacroiliac joint involvement in psoriatic arthritis - MRI, radiographic and clinical findings in 581 European routine care patients.

Nora Vladimirova, Anna Ef Hadsbjerg, Simon Krabbe, Adrian Ciurea, Kristýna Bubová, Monika Gregová, Michael J Nissen, Burkhard Möller, Raphael Micheroli, Susanne J Pedersen and 16 more

Abstract read
In one paragraph

Article in Arthritis research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Nora Vladimirova *COPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark. Nora.borislavova.vladimirova@regionh.dk.
Anna Ef HadsbjergCOPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.
Simon KrabbeCOPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.
Adrian CiureaDepartment of Rheumatology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Kristýna BubováInstitute of Rheumatology, Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Monika GregováInstitute of Rheumatology, Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Michael J NissenRheumatology Department, Geneva University Hospital, Geneva, Switzerland.
Burkhard MöllerDepartment of Rheumatology and Immunology, Inselspital, University Hospital Bern, Bern, Switzerland.
Raphael MicheroliDepartment of Rheumatology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Susanne J PedersenCOPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.
Jakub ZávadaInstitute of Rheumatology, Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Ziga SnojInstitute of Radiology, UMC Ljubljana, Ljubljana, Slovenia.
Karlo PintaricInstitute of Radiology, UMC Ljubljana, Ljubljana, Slovenia.
Bjorn GudbjornssonCentre for Rheumatology Research, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland.
Ziga RotarDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Iris EshedDepartment of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer affiliated with School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Iwona Sudol-SzopinskaDepartment of Radiology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Kasper GosvigDepartment of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark.
Torsten DiekhoffDepartment of Radiology, Charité - Universitätsmedizin Berlin, Humboldt- Universität zu Berlin, Freie Universität Berlin, Campus Mitte, Berlin, Germany.
Robert Gw LambertDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada.
Manouk de HoogeDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, USA.
Maurice DonzallazDepartment of Rheumatology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Alexander BernatschekDepartment of Rheumatology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
Merete Lund HetlandCOPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.
Lykke M Ørnbjerg *COPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.
Mikkel Østergaard *COPECARE, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, DK-2600, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAxial involvement in psoriatic arthritis (axPsA) is associated with more severe disease and increased pain, yet no consensus definition of axPsA exists. This study aims to describe the occurrence and characteristics of MRI and radiographic sacroiliac joint (SIJ) involvement in a European PsA cohort.

methodsPatients with a clinical diagnosis of PsA or of axial spondyloarthritis with psoriasis and available routine care SIJ MRIs were included from five European registries in the EuroSpA collaboration. SIJ MRIs and radiographs were centrally assessed for inflammatory and structural lesions, differential diagnoses, and globally evaluated for SpA-indicative findings.

resultsAmong 581 PsA patients (mean age 45 years, 47% male), 31% exhibited SpA-indicative SIJ-MRI findings (MRI-axPsA). In MRI-axPsA patients, the most common lesions were bone marrow edema (BME) (69%), erosions (68%), and fat lesions (58%), generally present bilaterally. BME ≥ 1 cm, inflammation in an erosion cavity, capsulitis, fat lesions ≥ 1 cm, backfill, and ankylosis were observed almost exclusively in MRI-AxPsA patients. Differential diagnoses included osteitis condensans ilii (8%), probable strain-related BME (11%) and degenerative disease (16%). Among 259 patients with radiographs, 29% met the radiographic mNY criteria for ankylosing spondylitis and 38% had SpA-indicative MRI findings. Male sex, HLA-B27 positivity, elevated CRP and history of inflammatory back pain (but not current back pain) were independently associated with MRI-detected axial involvement.

conclusionIn this large European cohort, one-third of routine care PsA patients had axial involvement, based on global SIJ MRI assessment. The study supports incorporating MRI into the future definition of axPsA to enable early identification.

Indexed as

Arthritis, PsoriaticMagnetic Resonance ImagingSacroiliac JointAdultAxial SpondyloarthritisCohort StudiesEuropeFemaleHumansMaleMiddle AgedRadiographyRegistriesAxial psoriatic arthritisAxial spondyloarthritisImagingMagnetic resonance imaging

Identifiers

PMID41023760
PMCPMC12482180

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