ArticleJournal of ovarian research2025
Impact of surgical modalities on the survival of stage I adult-type ovarian granulosa cell tumor: a comprehensive analysis of 101 cases.
Article in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundOnly small-sample retrospective studies have been performed to assess the efficacy of current treatment modalities for adult-type ovarian granulosa cell tumor. Therefore, we retrospectively evaluated patients with stage I AGCT admitted to our center over the past two decades and systematically analyzed the impact of different surgical modalities on the survival of these patients.
methodsAll patients with stage I AGCT treated in Sun Yat-sen University Cancer Center from May 1998 to April 2020 were enrolled and analyzed in this retrospective study.
resultsA total of 101 patients with stage I AGCT were identified, among whom 49 were stage Ia and 52 were stage Ic. The median follow up was 47.7 months. The 10-year cancer specific survival (CSS) and disease-free survival (DFS) rates were 90% and 53%, respectively. Multivariate analysis showed that only surgical extent (conservative vs. radical, HR: 2.738, p-value = 0.034) was an independent prognostic factor for disease-free survival. Subgroup analysis suggested that both surgical extent and surgical approach had a significant impact on the disease-free survival of patients with stage Ic (conservative vs. radical, HR: 4.021, p-value = 0.007; laparoscopic vs. open, HR: 2.926, p-value = 0.035) and tumor larger than 5 cm (conservative vs. radical, HR: 4.437, p-value = 0.001; laparoscopic vs. open, HR: 3.367, p-value = 0.006).
conclusionsPatients with stage I AGCT generally have a favorable prognosis. Surgical extent is an independent prognostic factor. For high risk patients with stage Ic disease or tumor larger than 5 cm, our study supports the selection of radical and open surgery as a potentially preferred option.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.