ArticleBMC anesthesiology2025
Association of transversus abdominis plane block (TAPB) with postoperative delirium (POD) in elderly patients undergoing major gastrointestinal surgery: a retrospective cohort study.
Article in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06829108 (Association of Transversus Abdominis Plane Block), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association of Transversus Abdominis Plane Block (TAPB) with Postoperative Delirium (POD) in Elderly Patients Undergoing Major Gastrointestinal Surgery: a Retrospective Cohort Study
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8 authors.
Funding
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Abstract
backgroundPostoperative delirium (POD) is one of the most prevalent complications in elderly surgical patients. This study aimed to assess whether the use of transversus abdominis plane block (TAPB) is associated with a reduced incidence of POD in this patient population.
methodsIn this retrospective cohort study (January 2016 to March 2022), we analyzed elderly patients (≥ 65 years) who underwent major gastrointestinal surgery. The association between TAPB and POD was evaluated using multivariate logistic regression, propensity score matching (PSM), inverse probability of treatment weighting (IPTW), and subgroup analyses.
resultsAmong 5,220 patients, the incidence of POD was significantly lower in patients receiving TAPB. This protective effect was consistently demonstrated in Multivariate regression analysis, OR was 0.351 (95% CI 0.163 to 0.663, P = 0.003). Consistent findings emerged after PSM (P = 0.007) and IPTW (P < 0.001) adjustment. TAPB was also associated with significantly reduced sufentanil requirements (P < 0.001) and shorter hospital length of stay (P < 0.001). However, 30-day postoperative mortality did not differ significantly between groups. Subgroup analyses stratified by age, sex, albumin, surgical site, Body mass index (BMI), and dexmedetomidine demonstrated no significant interaction effects across all variables (P-interaction > 0.05).
conclusionsCurrent evidence suggests that the use of TAPB is significantly associated with a reduced incidence of POD in elderly patients undergoing major gastrointestinal surgery.
trial registrationThe trial was registered on ClinicalTrials.gov on February 14, 2025, with the identifier NCT06829108.
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