ArticleBMC plant biology2025
Genome-wide identification of GhEDS1 gene family members in cotton and expression analysis in response to biotic and abiotic stresses.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Genome-wide identification and characterization of the glutaredoxin (GRX) family genes in wild soybean and their expression dynamics under salt and alkali conditions.Molecular biology reports · 2026Article
- Article
- Transcriptional and post-transcriptional regulatory networks controlling cotton fibre development.Plant molecular biology · 2026Review
- Genome-wide identification and functional characterisation of the EDS1 gene family reveals evolutionary conservation and stress-responsive regulatory roles in barley.Scientific reports · 2026Article
- Arabica coffee SBP transcription factor family members respond to brown leaf spot stress by regulating their expression.BMC plant biology · 2026Article
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7 authors.
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Abstract
backgroundEnhanced Disease Susceptibility 1 (EDS1) genes are central regulators of plant immunity and abiotic stress responses. Although well studied in model species, their genome-wide characterisation in cotton (Gossypium spp.) remains lacking.
resultsWe identified 268 putative EDS1 genes across four Gossypium species (G. hirsutum, G. barbadense, G. arboreum, and G. raimondii) using HMMER-based domain searches. Phylogenetic analysis grouped the genes into five subfamilies, reflecting both conserved ancestry and subgenome-specific diversification. Chromosomal mapping, collinearity, and Ka/Ks analyses revealed that segmental and whole-genome duplications were the primary drivers of expansion, with most duplicates under purifying selection. Promoter analysis using PlantCARE uncovered cis-regulatory elements responsive to abscisic acid, jasmonic acid, drought (MBS), and light signals (G-box). miRNA target prediction via psRNATarget revealed ghr-miR414 as a key regulator targeting multiple GhEDS1 transcripts. Functional enrichment indicated roles in lipid metabolism and ubiquitin-mediated proteolysis. Finally, RNA-seq data and qRT-PCR confirmed that GhEDS1A-13, GhEDS1D-57, and GhEDS1D-48 were significantly upregulated under PEG-induced drought stress, implicating them in ABA-linked stress adaptation.
conclusionsThis study provides the first comprehensive characterisation of the EDS1 gene family in cotton, highlighting its evolutionary dynamics, regulatory complexity, and potential in improving drought tolerance through molecular breeding.
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