Evidence map›Paper›PMID 41023624›Full record

ArticleMolecular medicine (Cambridge, Mass.)2025

LAG-3 palmitoylation-inducing dysfunction of decidual CD4

Liyuan Cui, Fengrun Sun, Xinhang Meng, Yujie Luo, Jinfeng Qian, Songcun Wang

Abstract read
In one paragraph

Article in Molecular medicine (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liyuan Cui *Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road.
Fengrun Sun *Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road.
Xinhang Meng *Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road.
Yujie LuoLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road.
Jinfeng QianLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road. qjf2003@163.com.
Songcun WangLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, P.R. China, 128 Shenyang Road. songcunwang@fudan.edu.cn.

Funding

National Key Research and Development Program of China 2023YFC2705403National Nature Science Foundation of China 32470992 and 82201852Special Youth Project for Clinical Research in Health Industry of Shanghai Municipal Health Commission 20224Y0005
6 · The paper itself

Abstract

Recurrent pregnancy loss (RPL) profoundly impacts not only the physical health but also the psychological well-being of women. Despite its profound effects, the underlying pathophysiological mechanisms of RPL remain largely elusive, with few discernible warning signs. Lymphocyte activation gene-3 (LAG-3) is a crucial immune checkpoint that modulates immune responses during infection and tumor. In the present study, we examined the expression of LAG-3 on CD4

Indexed as

Abortion, HabitualAntigens, CDCD4-Positive T-LymphocytesDeciduaAdultCytokinesFemaleHumansLipoylationLymphocyte Activation Gene 3 ProteinPregnancyAntigens, CDCytokinesLag3 protein, humanLymphocyte Activation Gene 3 ProteinDecidual CD4+T cellsLAG-3PalmitoylationPregnancyRecurrent pregnancy loss

Identifiers

PMID41023624
PMCPMC12482660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.