Evidence map›Paper›PMID 41023528›Full record

ReviewDermatology and therapy2025

The Burden of Alopecia Areata and Management with Baricitinib in the United Arab Emirates: A Narrative Review.

Hussein Abdel Dayem, Anwar Al Hammadi, Ashraf Reda, Fatima Albreiki, Ayman Al Naeem, Ahmed Ameen, Mohamed Ahmed, Huda Rajab Ali, Mohamed Elrayes, Gozde Senay and 1 more

Abstract readReview
In one paragraph

Review in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hussein Abdel DayemMediclinic, Al-Noor Hospital, Abu Dhabi, United Arab Emirates. h_abdel.dayem@yahoo.com.
Anwar Al HammadiDermaMed Clinic, Dubai, United Arab Emirates.
Ashraf RedaMediclinic Welcare Hospital, Dubai, United Arab Emirates.
Fatima AlbreikiTawam Hospital, Al Ain, United Arab Emirates.
Ayman Al NaeemIbrahim Bin Hamad Obaidullah Hospital, Ras Al Khaimah, United Arab Emirates.
Ahmed AmeenNMC Specialty Hospital, Abu Dhabi, United Arab Emirates.
Mohamed AhmedRashid Hospital, Dubai, United Arab Emirates.
Huda Rajab AliAbu Dhabi Healthcare Company (SEHA), Abu Dhabi, United Arab Emirates.
Mohamed ElrayesEli Lilly and Company, Dubai, United Arab Emirates.
Gozde SenayEli Lilly and Company, Dubai, United Arab Emirates.
Muna Al MurrawiDr. Muna AlMurrawi Medical Center, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia areata is an inflammatory autoimmune disease that presents as non-scarring hair loss in adults and children and causes substantial psychological distress, economic burden, and reduced quality of life for those affected. Although steroids and immunosuppressants are common treatments for alopecia areata, results from studies of Janus kinase inhibitors in the systemic management of alopecia areata, including those from long-term efficacy and safety studies on the Janus kinase 1/2 inhibitor baricitinib, show promising results. Despite alopecia areata placing a burden on healthcare systems in the Middle East, published data on the overall prevalence, patient characteristics, and treatment landscape for alopecia areata across the region are sparse, and a lack of approved therapies and insufficient access to treatment are treatment obstacles. Herein, we describe the burden of alopecia areata on patients and healthcare systems, review publications from the United Arab Emirates (UAE) on alopecia areata, highlight gaps in the data, and review clinical trial publications on the management of alopecia areata with baricitinib, the first Janus kinase inhibitor approved for the treatment of alopecia areata in the UAE. A regional expert assessment of the burden of alopecia areata and unmet medical needs in the UAE is provided, along with an expert opinion on treating patients with severe alopecia areata.

Indexed as

Alopecia areataJanus kinase (JAK) inhibitorMiddle EastUnited Arab Emirates

Identifiers

PMID41023528
PMCPMC12619884

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.